All Skin Care Products

All the skin care and anti-aging products listed here are supported by one or more clinical studies with human participants.

All Products

AHAVA Dead Sea Osmoter Concentrate

By delivering concentrated Dead Sea minerals to the skin, the AHAVA Dead Sea Osmoter Concentrate protects, rehydrates and smooths the complexion.

AHAVA Dermud

AHAVA's Dermud is a patented skin preparation enriched with Dead Sea minerals and vitamin antioxidants that protect the skin from UV damage.

AHAVA Extreme

Powered by a unique complex of natural actives from the extreme environments of the Dead Sea and the Himalayan Mountains, the AHAVA Extreme Day Cream and Extreme Night Treatment have...

Alyria Intense Wrinkle Correction

Alyria Intense Wrinkle Correction can produce conspicuous improvements in the number, length and depth of wrinkles in the crow's feet area within 3 months of use.

Aquaphor Healing Ointment

The petrolatum-based Aquaphor Healing Ointment is a an effective skin protectant and moisturizer that soothes chapped, irritated skin. It is used as standard therapy by many physicians for post-operative wound...

Aveeno Positively Radiant Skin Daily Moisturizer

Aveeno Positively Radiant Skin Daily Moisturizer contains active ingredients from soy that enables it to effectively improve skin clarity, skin tone, skin texture and skin smoothness.

Aveeno Skin Relief Moisturizing Lotion

Aveeno's Skin Relief Moisturizing Lotion is excellent at relieving the skin itching associated with xerosis, or abnormally dry skin. It does so by reinforcing the skin barrier, and by intensely...

Avène Anti-wrinkle Concentrate

The Anti-wrinkle Concentrate seems to works well with Avène Eluage Cream, reducing wrinkles in many areas of the face, as well as improving skin hydration, colour, elasticity and the evenness...

Avène Diacnéal

Avène Diacnéal is very effective in treating acne, and may even amplify the efficiency of other anti-acne treatments used by patients at the same time.

Avène Eluage Cream

The Eluage Cream, when used together with Avène's Anti-wrinkle Concentrate, seems to have strong effects in moisturizing the skin, and also appears to smooth, lighten and increase skin elasticity and...

Avène Thermal Spring Water

Avène Thermal Spring Water is useful as adjunctive care for reducing inflammation and discomfort after aggressive dermatology procedures such as laser resurfacing or photodynamic therapy.

Avène Ysthéal Cream

Avène Ysthéal Cream helps to reduce wrinkles and smooth the skin as effectively as a tretinoin cream, but with better tolerability.

Bionect Cream

Bionect Cream, a formulation containing 0.2% sodium hyaluronate, appears to be effective in reducing the signs and symptoms of rosacea even over a short treatment period of 4 weeks.

Bionect Hydrogel

Bionect Hydrogel appears to be useful for treating facial seborrheic dermatitis, but additional blinded studies with a larger number of subjects are needed to delineate its efficacy and safety.

Boots No7 Protect & Perfect Intense Beauty Serum

The Protect and Perfect Intense Beauty Serum may reduce wrinkles on the face if applied daily for 12 months, but the evidence could be better.

Cellex-C High Potency Serum

Though the study was on a small group, the Cellex-C serum containing vitamin C appears to be effective in improving wrinkles, skin colour, roughness and looseness of the skin with...


C'ensil contains a high concentration of ascorbic acid, which is known for its effect in lightening skin. It may be effective in treating skin affected by melasma.

Cetaphil DermaControl Moisturizer

Cetaphil's DermaControl Moisturizer is specially formulated for acne-prone and acne-affected skin. It controls skin sebum levels and thus helps reduce facial shine, and helps diminish the irritation caused by topical...

Cetaphil Gentle Skin Cleanser

As its name suggests, Cetaphil Gentle Skin Cleanser is a mild, non-irritating formulation that can be a good choice for those with skin conditions such as rosacea.

Cetaphil Moisturizing Cream

Cetaphil Moisturizing Cream soothes dry, sensitive skin by improving skin hydration, skin roughness and skin sensitivity. It helps repair the skin barrier, making it useful for those suffering from acne,...

Cetaphil RestoraDerm Moisturizer

Cetaphil RestoraDerm Moisturizer is a skin barrier repair lotion that contains a ceramide precursor and components of the skin's natural moisturizing factors, designed to help normalize the compromised skin barrier...

Concentré Anti-taches Nuit

Concentré Anti-taches Nuit by Parfums Christian Dior is a skin whitening product that has been clinically proven to inhibit the darkening of the skin as a result of UV exposure....


Dermyn contains Tricutan, a combination of herbal extracts plus the DMAE molecule that is responsible for its skin firming effects. As a result, its use may be able to delay...


Elidel cream is very effective in treating atopic dermatitis in adults and children. Unlike treatment with corticosteroids, which is associated with numerous adverse effects, it is also very safe and...

elure Advanced Skin Lightening

elure's Advanced Skin Lightening products are effective in lightening the skin of Asian women, and bring about significant changes after just 1 month of treatment.


The Hyalogy product range appears to be effective in improving wrinkles as well as the moisturization and elasticity of the skin, but larger, controlled studies are needed to validate its...

Hylatopic Plus

Hylatopic Plus is a prescription product that appears to be very efficient and safe in treating atopic dermatitis.

Imedeen Derma One

Imedeen Derma One, previously known as Imedeen Classic, is an evolution of the original formulation that has been tested multiple times over the past 20+ years for its beneficial effects...

Imedeen Prime Renewal

Imedeen Prime Renewal helps post-menopausal women combat the effects of a decline in skin collagen. It diminishes wrinkles, fades mottled hyperpigmentation and maintains the firmness of the skin.


Isotrexol has good anti-wrinkle effects in those aged above 50, and may also help improve eye bags and sallow skin.


Kerasal contains salicyclic acid and urea, which have been widely used as topical treatments for dry skin for decades.


There is modest evidence to show that Kinerase may be useful in reducing facial redness, and in improving the colour and roughness of the skin.


Lac-Hydrin contains 12% ammonium lactate, a strong moisturizing agent, and is therefore very effective in treating abnormally dry and scaly skin conditions such as xerosis.


Apart from its potent moisturizing effect on the skin, Lactinol is also very well-liked by patients, which can lead to greater patient adherence and usage.

La Roche-Posay Active C

La Roche-Posay Active C appears to provide good anti-wrinkle benefits, as evidenced by a double-blinded and controlled, albeit small, study.

Lumixyl Topical Brightening System

The Lumixyl Topical Brightening System is a very good at treating mild to moderate cases of melasma, and can be considered as an option especially for those suffering from recalcitrant...

Neova Complex Cu3 Intensive Tissue Repair Crème

Neova's Tissue Repair Crème appears to provide a superior improvement in photoaged skin when used with other copper tripeptide-containing products following laser treatment.

Obagi Condition and Enhance System

The Obagi Condition and Enhance System does appear to be a complementary treatment modality to non-surgical facial rejuvenation procedures like IPL treatment and Botox, providing even greater reductions in hyperpigmentation...

Obagi-C Rx System

There is modest evidence that the Obagi-C Rx System helps to brighten, tighten and smooth skin, but it contains hydroquinone, a substance of questionable safety.

Obagi ELASTIderm Décolletage System

The Obagi ELASTIderm Wrinkle Reducing Lotion and Skin Lightening Complex appear to have good effects in improving wrinkling, hyperpigmentation and helps tighten the skin when applied to the neck and...

Obagi Nu-Derm

The Obagi Nu-Derm regimen is not only effective in treating epidermal melasma, but can also improve wrinkles, smooth and firm the skin when used in combination with tretinoin cream.

Olay Professional Pro-X Intensive Wrinkle Protocol

The Olay Professional Pro-X Age Repair Lotion, Wrinkle Smoothing Cream and Deep Wrinkle Treatment products can smooth wrinkles and improve the texture of the skin without adversely affecting the skin...

Olay Total Effects 7X Visible Anti-Aging Vitamin Complex Fragrance Free

Those suffering from rosacea can benefit by adding this niacinamide-containing moisturizer to their regular skin therapy, as it enhances the barrier function of the skin and hence reduces skin sensitivity,...

Perfectil Platinum

The skin is prone to seasonal changes during winter, especially in exposed areas. Daily supplementation wtih Perfectil Platinum during the winter months can help prevent the skin from becoming wrinkled,...


Elizabeth Arden's Prevage contains 0.5% idebenone, a potent antioxidant and numerous moisturizing ingredients that account for its strong hydrating and skin smoothing effects.

Prevage MD

Prevage MD is an anti-aging treatment that is capable of smoothing photoaged skin and diminishing facial fine lines and wrinkles. It also leads to a striking increase in skin moisturization.


Renova is an effective single treatment for wrinkles, owing to its tretinoin content. Tretinoin has well-established effects in smoothing the skin.


The tretinoin found in Retin-A's formulation enables it to reduce the length and depth of wrinkles, though only slightly.

Retriderm Serum

Retriderm Serum provides more modest improvements to the skin than Retriderm ULTRA due to its lower retinol concentration, but side effects such as dryness, burning, itching and redness are minimal,...

Retriderm ULTRA

The 1% retinol found in Retriderm ULTRA appears to markedly improve wrinkles on the face, brighten and smooth skin as well as make the skin more supple and elastic.


Preliminary research indicates that the combination of the RevaléSkin Facial Cleanser, Day and Night Creams can significantly improve photodamaged skin, including wrinkles, roughness and pigmentation.


There is good evidence that these capsules containing resveratrol and procyanidines are effective in smoothing wrinkles, lightening age spots, hydrating the skin and improving its elasticity.

RoC Retin-OX

RoC's Retin-OX has robust anti-wrinkle effects, even when used over relatively short durations (e.g. 8 weeks).

SkinCeuticals Advanced Pigment Corrector

SkinCeuticals' Advanced Pigment Corrector contains a promising mix of ingredients for improving aged skin and may smooth, lighten and make the skin more supple.

SkinMedica Lytera Skin Brightening Complex

SkinMedica's Lytera Skin Brightening Complex is a hydroquinone-free product that seems live up to its claim, due to its formulation which includes several active ingredients that have proven lightening effects.


Originally meant for treating stretch marks, StriVectin-SD quickly gained favour for its effectiveness in easing fine lines, wrinkles and crow's feet upon its release.


Vivida supplements seem to be strikingly good at reversing the signs of skin aging. It boosts skin thickness, elasticity and moisture, and is also effective at tightening loose, sagging skin,...

Vivida Cream

Like Vivida supplements, Vivida Cream appears to be very effective at bringing about improvements to damaged skin, especially with regards to skin thickness and elasticity, though the mechanisms through which...