AHAVA Dead Sea Osmoter Concentrate

By delivering concentrated Dead Sea minerals to the skin, the AHAVA Dead Sea Osmoter Concentrate protects, rehydrates and smooths the complexion.

Images


Effects


Grade Level of Evidence
A Double-blind, controlled study with more than 50 participants.
B Controlled study that is single-blind or has less than 50 participants.
C Controlled or comparative study.
D Uncontrolled or observational study.
Grade Effect Size of Effect Comments

B

Wrinkle treatment

Strong

Enhanced the anti-wrinkle effect of an anti-wrinkle gel by 46%.

C

Increased skin hydration

Moderate

Moisturizes the skin by raising the expression of aquaporin-3, an important water/glycerol transporter.

D

Photoprotection

Mild

Abolishes the changes in pro-apoptotic activity induced by UVB radiation.

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Ingredients


Aqua (Mineral Spring Water), PVP, Maris Aqua (Dead Sea Water), Cyclomethicone, Dimethicone, Aloe Barbadensis Leaf Juice, Glycerin, Isodecyl Isononanoate, Diisobutyl Adipate, Caprylyl Methicone, Butylene Glycol, Sodium Lactate, Trehalose, Dimethiconol, PEG-12 Dimethicone/PPG-20 Crosspolymer, Phenoxyethanol, Citrus Aurantium Amara Fruit Extract, Bisabolol, Squalene (Phytosqualene), Argania Spinosa Kernel Oil, Parfum (Fragrance), Sigesbeckia Orientalis Extract, Hydroxyethyl Acrylate\Sodium Acryloydimethyl Taurate Copolymer, Rabdosia Rubescens Extract, Sodium Hyaluronate, Citric Acid, Lactic Acid, Benzotriazolyl Dodecyl p-Cresol, Helianthus Annuus (Sunflower ) Seed Oil, Melissa Officinalis Leaf Extract, Polyglyceryl-3 polyricinoleate, Citrus Reticulata Fruit Extract, Tris (Tetramethyl Hydroxypiperidinol) Citrate, Sodium Benzotriazolyl Butylphenol Sulfonate, Laminaria Digitata Extract, Ascorbic Acid, Glucosyl Hesperidin, Olea Europaea (Olive) Leaf Extract, Fructose, Vitis Vinifera (Grape) Seed Extract, Phosphatidylcholine, Camellia Sinensis Leaf Extract, Biosaccharide Gum-1, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocin
NAME ANTIOXIDANT UV PROTECTION COMEDOGENIC IRRITANT SAFETY
AQUA (SOLVENT) 0 0 ALLOWED (SOURCE)
PVP (ANTISTATIC, BINDING, EMULSION STABILISING, FILM FORMING, HAIR FIXING, VISCOSITY CONTROLLING) 0 (SEE SOURCES) 0 (SEE SOURCES) ALLOWED (SOURCE)
MARIS AQUA (SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
CYCLOMETHICONE (ANTISTATIC, EMOLLIENT, HAIR CONDITIONING, HUMECTANT, SOLVENT, VISCOSITY CONTROLLING) 0 (SEE SOURCES) 0 (SEE SOURCES) ALLOWED (SOURCE)
DIMETHICONE (ANTIFOAMING, EMOLLIENT, SKIN CONDITIONING, SKIN PROTECTING) 1 (SEE SOURCES) 0 (SEE SOURCES) ALLOWED (SOURCE)
ALOE BARBADENSIS LEAF JUICE (SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
GLYCERIN (DENATURANT, HUMECTANT, PERFUMING, SOLVENT) 0 (SEE SOURCES) 0 (SEE SOURCES) ALLOWED (SOURCE)
ISODECYL ISONONANOATE (ANTISTATIC, EMOLLIENT, SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
DIISOBUTYL ADIPATE (EMOLLIENT, MASKING, PLASTICISER, SKIN CONDITIONING, SOLVENT) NO DATA NO DATA ALLOWED (SOURCE)
CAPRYLYL METHICONE (SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
BUTYLENE GLYCOL (HUMECTANT, MASKING, SKIN CONDITIONING, SOLVENT, VISCOSITY CONTROLLING) 1 (SEE SOURCES) 0 (SEE SOURCES) ALLOWED (SOURCE)
SODIUM LACTATE (BUFFERING, HUMECTANT, KERATOLYTIC) NO DATA NO DATA ALLOWED (SOURCE)
TREHALOSE (HUMECTANT, MOISTURISING) NO DATA NO DATA ALLOWED (SOURCE)
DIMETHICONOL (ANTIFOAMING, EMOLLIENT, MOISTURISING) NO DATA NO DATA ALLOWED (SOURCE)
PEG-12 DIMETHICONE/PPG-20 CROSSPOLYMER (EMOLLIENT, SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
PHENOXYETHANOL (PRESERVATIVE) NO DATA NO DATA ALLOWED (SOURCE)
CITRUS AURANTIUM AMARA FRUIT EXTRACT (SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
BISABOLOL (MASKING, SKIN CONDITIONING, SOOTHING) NO DATA NO DATA ALLOWED (SOURCE)
SQUALENE (ANTISTATIC, EMOLLIENT, HAIR CONDITIONING, REFATTING, SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
ARGANIA SPINOSA KERNEL OIL (EMOLLIENT, SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
PARFUM (DEODORANT, MASKING, PERFUMING) NO DATA NO DATA ALLOWED (SOURCE)
SIGESBECKIA ORIENTALIS EXTRACT (SKIN CONDITIONING, TONIC) NO DATA NO DATA ALLOWED (SOURCE)
HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER (EMULSION STABILISING, VISCOSITY CONTROLLING) NO DATA NO DATA ALLOWED (SOURCE)
RABDOSIA RUBESCENS EXTRACT (SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
SODIUM HYALURONATE (HUMECTANT, SKIN CONDITIONING) 0 (SEE SOURCES) 0 (SEE SOURCES) ALLOWED (SOURCE)
CITRIC ACID (BUFFERING, CHELATING, MASKING) NO DATA NO DATA ALLOWED (SOURCE)
LACTIC ACID (BUFFERING, HUMECTANT, SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
BENZOTRIAZOLYL DODECYL P-CRESOL (UV ABSORBER) NO DATA NO DATA ALLOWED (SOURCE)
HELIANTHUS ANNUUS (SUNFLOWER) SEED BUTTER (EMOLLIENT, SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
MELISSA OFFICINALIS LEAF EXTRACT (SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
POLYGLYCERYL-3 POLYRICINOLEATE (EMULSIFYING, VISCOSITY CONTROLLING) NO DATA NO DATA ALLOWED (SOURCE)
CITRUS RETICULATA FRUIT EXTRACT (SKIN PROTECTING) NO DATA NO DATA RESTRICTED (SOURCE)
TRIS(TETRAMETHYLHYDROXYPIPERIDINOL) CITRATE (UV ABSORBER) NO DATA NO DATA ALLOWED (SOURCE)
SODIUM BENZOTRIAZOLYL BUTYLPHENOL SULFONATE (UV ABSORBER) NO DATA NO DATA ALLOWED (SOURCE)
LAMINARIA DIGITATA EXTRACT (SKIN PROTECTING) NO DATA NO DATA ALLOWED (SOURCE)
ASCORBIC ACID (ANTIOXIDANT, BUFFERING, MASKING, SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
GLUCOSYL HESPERIDIN (HUMECTANT, SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
OLEA EUROPAEA LEAF EXTRACT (PERFUMING, SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
FRUCTOSE (HUMECTANT) NO DATA NO DATA ALLOWED (SOURCE)
VITIS VINIFERA SEED EXTRACT (ANTIDANDRUFF, ANTIMICROBIAL, ANTIOXIDANT, ORAL CARE, SKIN PROTECTING, UV ABSORBER) NO DATA NO DATA ALLOWED (SOURCE)
PHOSPHATIDYLCHOLINE (EMULSIFYING, SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
CAMELLIA SINENSIS LEAF EXTRACT (ANTIMICROBIAL, ANTIOXIDANT, ASTRINGENT, EMOLLIENT, HUMECTANT, MASKING, ORAL CARE, SKIN CONDITIONING, SKIN PROTECTING, TONIC, UV ABSORBER) NO DATA NO DATA ALLOWED (SOURCE)
BIOSACCHARIDE GUM-1 (SKIN CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE (ANTIOXIDANT) NO DATA NO DATA ALLOWED (SOURCE)

Clinical Studies


Protective Effects of a Novel Preparation Consists of Concentrated Dead Sea Water and Natural Plants Extracts against Skin Photo-Damage.

Products

AHAVA Dead Sea Osmoter Concentrate

Regular moisturizer

Trial Design

Controlled

Duration

24 hours

Subjects

35 women aged at least 18 years, who had a lack of skin tone homogeneity or slight skin discolorations, and with dehydrated skin in the test area

Regimen

Subjects applied the Dead Sea Osmoter Concentrate to one area on their forearm, the regular moisturizer to a second area, and both products on a third area. A fourth area served as a control.

Methods of Assessment

Clinical measurements of skin hydration with a corneometer

Side Effects

No unwanted skin reactions were reported.

Conflicts of Interest

3 of the 7 authors worked for AHAVA-Dead Sea Laboratories.

Effects observed in this study:

Clinical trial: 30 minutes after application, the area where only the AHAVA Dead Sea Osmoter Concentrate had been applied was 105% more hydrated, the area where only the moisturizer had been applied was 90% more hydrated, and the area where both treatments had been applied was 136% more hydrated. After 8 hours, the increases in skin hydration were 50%, 41% and 51% respectively. By 24 hours after treatment, only the areas where the AHAVA Dead Sea Osmoter Concentrate or where both products had been applied had significantly elevated skin hydration (17% and 21%) compared to the control area.

Ex-vivo experiments: Ex vivo human skin specimens saw a significant enhancement in the activity of the pro-apoptotic caspase 3 enzyme and a decrease in the activity of the proteosome 20S subunit following UVB irradiation. The former was markedly reduced by 66% and the latter was prevented when the skin was pre-treated with AHAVA Dead Sea Osmoter Concentrate. Furthermore, the level of aquaporin-3 was also 88% higher in irradiated samples that had been treated that in irradiated untreated samples. Aquaporin-3 expression was also increased by 44% in non-irradiated samples that had been treated, compared to non-irradiated and untreated controls.

Skin smoothing effects of Dead Sea minerals: comparative profilometric evaluation of skin surface.

Products

Anti-wrinkle gel with 1% AHAVA Dead Sea Osmoter Concentrate

Anti-wrinkle gel without 1% AHAVA Dead Sea Osmoter Concentrate

Placebo gel

Trial Design

Double-blind, placebo-controlled

Duration

4 weeks of treatment

Subjects

20 women aged 20-65, 10 with sensitive skin and 10 with normal skin.

Regimen

Subjects applied each preparation twice a day to both their left and right forearms

Methods of Assessment

Measurement of skin surface smoothness through computer-aided laser profilometry of silicone-based skin impressions

Side Effects

None reported

Conflicts of Interest

At least 1 of the 3 authors worked for AHAVA Dead Sea Laboratories.

Effects observed in this study:

The placebo gel reduced skin roughness by an average of 10.4%, the anti-wrinkle gel by an average of 27.8% and the anti-wrinkle gel containing 1% Dead Sea Osmoter Concentrate by an average of 40.7%. In other words, the same product with Dead Sea water was 46% more effective in smoothing the skin. Significant differences were found among the 3 groups.