Aveeno Skin Relief Moisturizing Lotion

Aveeno's Skin Relief Moisturizing Lotion is excellent at relieving the skin itching associated with xerosis, or abnormally dry skin. It does so by reinforcing the skin barrier, and by intensely moisturizing the skin.

Images


Effects


Grade Level of Evidence
A Double-blind, controlled study with more than 50 participants.
B Controlled study that is single-blind or has less than 50 participants.
C Controlled or comparative study.
D Uncontrolled or observational study.
Grade Effect Size of Effect Comments

D

Increased skin hydration

Strong

Enhances skin moisturization by 36% after just 1 week of treatment and an improvement of 46% after 3 weeks.

D

Enhanced barrier function

Mild

Leads to a slight decrease in skin pH, suggestive of a strengthened skin barrier.

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Ingredients


Aqua, Glycerin, Distearyldimonium Chloride, Petrolatum, Isopropyl Palmitate, Paraffinum Liquidum, Cetyl Alcohol, Dimethicone, Avena Sativa Kernel Flour, Menthol, Allantoin, Cera Microcristallina, Stearyl Alcohol, Myristyl Alcohol, Isopropyl Alcohol, Sodium Chloride, Paraffin, Benzyl Alcohol
NAME ANTIOXIDANT UV PROTECTION COMEDOGENIC IRRITANT SAFETY
AQUA (SOLVENT) 0 0 ALLOWED (SOURCE)
GLYCERIN (DENATURANT, HUMECTANT, PERFUMING, SOLVENT) 0 (SEE SOURCES) 0 (SEE SOURCES) ALLOWED (SOURCE)
DISTEARYLDIMONIUM CHLORIDE (ANTISTATIC, HAIR CONDITIONING) NO DATA NO DATA ALLOWED (SOURCE)
PETROLATUM (ANTISTATIC, EMOLLIENT) NO DATA NO DATA RESTRICTED (SOURCE)
ISOPROPYL PALMITATE (ANTISTATIC, BINDING, EMOLLIENT, PERFUMING, SKIN CONDITIONING, SOLVENT) 4 (SEE SOURCES) 1 (SEE SOURCES) ALLOWED (SOURCE)
PARAFFINUM LIQUIDUM (ANTISTATIC, EMOLLIENT, SKIN PROTECTING, SOLVENT) NO DATA NO DATA ALLOWED (SOURCE)
CETYL ALCOHOL (EMOLLIENT, EMULSIFYING, EMULSION STABILISING, FOAM BOOSTING, MASKING, OPACIFYING, SURFACTANT, VISCOSITY CONTROLLING) 3 (SEE SOURCES) 2 (SEE SOURCES) ALLOWED (SOURCE)
DIMETHICONE (ANTIFOAMING, EMOLLIENT, SKIN CONDITIONING, SKIN PROTECTING) 1 (SEE SOURCES) 0 (SEE SOURCES) ALLOWED (SOURCE)
AVENA SATIVA KERNEL FLOUR (ABRASIVE, ABSORBENT, BULKING, VISCOSITY CONTROLLING) NO DATA NO DATA ALLOWED (SOURCE)
MENTHOL (DENATURANT, MASKING, REFRESHING, SOOTHING) NO DATA NO DATA ALLOWED (SOURCE)
ALLANTOIN (SKIN CONDITIONING, SKIN PROTECTING, SOOTHING) 0 (SEE SOURCES) 0 (SEE SOURCES) ALLOWED (SOURCE)
CERA MICROCRISTALLINA (BINDING, EMULSION STABILISING, OPACIFYING, VISCOSITY CONTROLLING) NO DATA NO DATA ALLOWED (SOURCE)
STEARYL ALCOHOL (EMOLLIENT, EMULSIFYING, EMULSION STABILISING, FOAM BOOSTING, MASKING, OPACIFYING, REFATTING, SURFACTANT, VISCOSITY CONTROLLING) 2 (SEE SOURCES) 2 (SEE SOURCES) ALLOWED (SOURCE)
MYRISTYL ALCOHOL (EMOLLIENT, EMULSION STABILISING, FOAM BOOSTING, SKIN CONDITIONING, VISCOSITY CONTROLLING) 2 (SEE SOURCES) 4 (SEE SOURCES) ALLOWED (SOURCE)
ISOPROPYL ALCOHOL (ANTIFOAMING, PERFUMING, SOLVENT, VISCOSITY CONTROLLING) 0 (SEE SOURCES) 0 (SEE SOURCES) ALLOWED (SOURCE)
SODIUM CHLORIDE (BULKING, MASKING, ORAL CARE, VISCOSITY CONTROLLING) NO DATA NO DATA ALLOWED (SOURCE)
PARAFFIN (SKIN CONDITIONING, VISCOSITY CONTROLLING) NO DATA NO DATA ALLOWED (SOURCE)
BENZYL ALCOHOL (PERFUMING, PRESERVATIVE, SOLVENT, VISCOSITY CONTROLLING) NO DATA NO DATA RESTRICTED (SOURCE)

Clinical Studies


Clinical Trial on Aveeno Skin Relief Moisturizing Lotion in Patients with Itching Accompanied by Skin Lesions and Xerosis.

Products

Aveeno Skin Relief Moisturizing Lotion

Trial Design

Open, uncontrolled

Duration

3 weeks of treatment

Subjects

54 male and female patients with itching and xerosis. 13 patients also had erythema, 49 had desquamation, 30 had scratching lesions, 10 had lichenization, 28 had allergies, 12 had atopic dermatitis and 10 were in dialysis.

Regimen

Patients used Aveeno Skin Relief Moisturizing Lotion once daily, and were also allowed to use neutral cleansing.

Methods of Assessment

Clinical assessment of skin lesions and the presence of erythema, desquamation, scratching lesions and lichenization, scored on a 3-point scale.

Evaluation of photographs of skin lesions before and after treatment.

Skin hydration and pH measurements using a SM CM PH Combi 3 instrument.

Patient self-administered questionnaire for the evaluation of itching, with 10 questions each quantified using a visual analogue scale.

Side Effects

No intolerance reactions were reported.

Conflicts of Interest

None declared.

Effects observed in this study:

After 3 weeks of treatment, 52 out of the 54 patients (96%) had significant improvements of cutaneous lesions including erythema, scaling, scratching lesions, lichenification and pruritus. 48 of these patients (89%) had achieved complete regression of their cutaneous lesions and pruritus, while a partial remission was observed in 4 patients (7.4%).

The self-administered questionnaires revealed that pruritus declined significantly by 45% after the first week, and by 74% after 3 weeks of treatment. Skin hydration was similarly improved by 36% after 1 week of treatment, and by 46% after 3 weeks. pH measurements showed a simultaneous decrease of skin surface pH by 4% after the first week, and 6.3% by the end of the treatment period.

The 2 patients who experienced no improvement were both affected by advanced chronic renal failure, treated with hemodialysis.