Hydroquinone + Kojic Acid + Corticosteroid

Efficacy

Outcome				Grade		Effect		Evidence		Studies
Melasma				E		🠫 Slight		★★ Some		1 study 40 participants

Side Effects

Outcome			Effect		Frequency			Studies
Acne			⇧ Increase		5% (1 out of 20 participants)			1 study

Latest Research

Kojic Acid vis-a-vis its Combinations with Hydroquinone and Betamethasone Valerate in Melasma: A Randomized, Single Blind, Comparative Study of Efficacy and Safety (2013)