Fucose is a monosaccharide sugar that is found in many glycoproteins and glycolipids in the body (R). It can also be extracted from brown algae and bacteria (R). Fucose is part of a class of sugars known as deoxy sugars, which have had one oxygen molecule removed from the sugar structure (R). It is often the terminal sugar on glycan chains attached to proteins and lipids, enabling it to play important roles in cell signaling, cell-cell interaction and cell-matrix interactions (R).
As a small molecule with a molecular weight of just 164.16 Daltons, fucose is likely able to penetrate the skin barrier (R). Indeed, it has been shown to penetrate rat skin quite quickly, reaching both the epidermis and the dermis within 1 hour after topical application (R).
| Outcome | Grade | Effect | Studies | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Skin Thickness |
D
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| Outcome | Grade | Effect | Studies | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cell Viability |
D
|
|
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| Elastic Fibres |
D
|
|
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| Fibronectin |
D
|
|
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| Elastase |
D
|
|
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| Tropoelastin |
D
|
|
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