Hyaluronic Acid + Panthenol + Thiamidol

Efficacy

Outcome				Grade		Effect		Evidence		Studies
Hyperpigmentation				C		🠫 Slight		★★ Some		1 study 47 participants
Melasma				E		🠫 Slight		★★ Some		1 study 47 participants

Side Effects

Outcome			Effect		Frequency			Studies
Contact Dermatitis			⇧ Increase		8% (2 out of 25 participants)			1 study

Latest Research

Efficacy and safety of topical isobutylamido thiazolyl resorcinol (Thiamidol) vs. 4% hydroquinone cream for facial melasma: an evaluator-blinded, randomized controlled trial (2021)