Efficacy and safety of topical isobutylamido thiazolyl resorcinol (Thiamidol) vs. 4% hydroquinone cream for facial melasma: an evaluator-blinded, randomized controlled trial

Efficacy

Intervention(s)		Outcome		Effect	Description
Hydroquinone		Hyperpigmentation		Decrease	Login to read descriptions for free
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Hyaluronic Acid + Panthenol + Thiamidol		Hyperpigmentation		Decrease	Login to read descriptions for free
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Hyaluronic Acid + Panthenol + Thiamidol		Melasma		Decrease	Login to read descriptions for free
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Hydroquinone		Melasma		Decrease	Login to read descriptions for free
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Side Effects

Intervention(s)		Outcome	Effect	Description
Hydroquinone		Contact Dermatitis	Increase	Login to read descriptions for free
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Hyaluronic Acid + Panthenol + Thiamidol		Contact Dermatitis	Increase	Login to read descriptions for free
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Hydroquinone		Pain	Increase	Login to read descriptions for free
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Hyaluronic Acid + Panthenol + Thiamidol		Pain	No Effect	Login to read descriptions for free
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Hydroquinone		Peeling	Increase	Login to read descriptions for free
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Hyaluronic Acid + Panthenol + Thiamidol		Peeling	No Effect	Login to read descriptions for free
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Hyaluronic Acid + Panthenol + Thiamidol		Skin Redness	No Effect	Login to read descriptions for free
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Hydroquinone		Skin Redness	Increase	Login to read descriptions for free
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Study Design

Subject Type

Human

Trial Design

Single-Blind, Randomised, Controlled

Trial Duration

90 days

Participants

50 (47 completed)

Age Range

18-50 years

Study Summary

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