Efficacy and safety of topical isobutylamido thiazolyl resorcinol (Thiamidol) vs. 4% hydroquinone cream for facial melasma: an evaluator-blinded, randomized controlled trial

Study Design

Subject Type

Human

Trial Design

Single-Blind, Randomised, Controlled

Trial Duration

90 days

Participants

50 (47 completed)

Age Range

18-50 years

Efficacy

Intervention(s)			Outcome		Method		Effect	Description
Hydroquinone			Hyperpigmentation		Colorimeter		🠫	Sign in to read for free
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Hyaluronic Acid + Panthenol + Thiamidol			Hyperpigmentation		Colorimeter		🠫	Sign in to read for free
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Hydroquinone			Melasma		Clinical grading		🠫	Sign in to read for free
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Hyaluronic Acid + Panthenol + Thiamidol			Melasma		Clinical grading		🠫	Sign in to read for free
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Side Effects

Intervention(s)			Outcome		Effect	Description
Hydroquinone			Contact Dermatitis		⇧	Sign in to read for free
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Hyaluronic Acid + Panthenol + Thiamidol			Contact Dermatitis		⇧	Sign in to read for free
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Hydroquinone			Peeling		⇧	Sign in to read for free
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Hyaluronic Acid + Panthenol + Thiamidol			Peeling		–	Sign in to read for free
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Hyaluronic Acid + Panthenol + Thiamidol			Skin Discomfort		–	Sign in to read for free
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Hydroquinone			Skin Discomfort		⇧	Sign in to read for free
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Hydroquinone			Skin Redness		⇧	Sign in to read for free
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Hyaluronic Acid + Panthenol + Thiamidol			Skin Redness		–	Sign in to read for free
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Study Summary

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