A double-blind randomized trial of 5% ascorbic acid vs. 4% hydroquinone in melasma

Study Design

Subject Type

Human

Trial Design

Double-Blind, Randomised, Controlled

Trial Duration

112 days

Participants

16 (15 completed)

Age Range

23-43 years

Efficacy

Intervention(s)			Outcome		Method		Effect	Description
Ascorbic Acid			Hyperpigmentation		Colorimeter		🠫	Sign in to read for free
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Hydroquinone			Hyperpigmentation		Colorimeter		🠫	Sign in to read for free
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Ascorbic Acid			Melasma		Clinical grading		🠫	Sign in to read for free
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Hydroquinone			Melasma		Clinical grading		🠫	Sign in to read for free
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Side Effects

Intervention(s)			Outcome		Effect	Description
Ascorbic Acid			Irritation		⇧	Sign in to read for free
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Hydroquinone			Irritation		⇧	Sign in to read for free
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Study Summary

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