In vitro antioxidant activity and in vivo efficacy of topical formulations containing vitamin C and its derivatives studied by non-invasive methods

Study Design

Subject Type

Human

Trial Design

Controlled

Trial Duration

28 days

Participants

40

Efficacy

Intervention(s)			Outcome		Method		Effect	Description
Ascorbyl Tetraisopalmitate			Skin Barrier Function		Tewameter		–	Sign in to read for free
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Ascorbic Acid			Skin Barrier Function		Tewameter		⇧	Sign in to read for free
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Magnesium Ascorbyl Phosphate			Skin Barrier Function		Tewameter		–	Sign in to read for free
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Ascorbic Acid			Skin Elasticity		Cutometer		–	Sign in to read for free
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Ascorbyl Tetraisopalmitate			Skin Elasticity		Cutometer		–	Sign in to read for free
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Magnesium Ascorbyl Phosphate			Skin Elasticity		Cutometer		–	Sign in to read for free
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Ascorbyl Tetraisopalmitate			Skin Hydration		Corneometer		⇧	Sign in to read for free
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Ascorbic Acid			Skin Hydration		Corneometer		⇧	Sign in to read for free
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Magnesium Ascorbyl Phosphate			Skin Hydration		Corneometer		⇧	Sign in to read for free
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Mechanisms

Intervention(s)			Outcome		Method		Effect	Description
Ascorbic Acid			Oxidation		Assay		🠫	Sign in to read for free
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Magnesium Ascorbyl Phosphate			Oxidation		Assay		🠫	Sign in to read for free
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Ascorbyl Tetraisopalmitate			Oxidation		Assay		🠫	Sign in to read for free
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Side Effects

Intervention(s)			Outcome		Effect	Description
Ascorbic Acid			Itching		–	Sign in to read for free
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Ascorbyl Tetraisopalmitate			Itching		–	Sign in to read for free
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Magnesium Ascorbyl Phosphate			Itching		–	Sign in to read for free
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Ascorbic Acid			Skin Redness		–	Sign in to read for free
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Magnesium Ascorbyl Phosphate			Skin Redness		–	Sign in to read for free
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Ascorbyl Tetraisopalmitate			Skin Redness		–	Sign in to read for free
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Study Summary

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