Skin Elasticity

A Novel Protection and Repair Skincare Regimen Shows Efficacy for Improving Environmental Skin Aging (2024)

Open-label topical application of tetrahexyldecyl ascorbate and acetyl zingerone containing serum improves the appearance of photoaging and uneven pigmentation (2024)

Efficacy of castor oil cream in treating infraorbital hyperpigmentation: An exploratory single-arm clinical trial (2024)

In Vitro and In Vivo Anti-Aging Effect of Coffee Berry Nanoliposomes (2023)

Restoration of Aging Body Skin: Evidence-Based Development of a Topical Formulation for Improving Body Skin Quality (2023)

Effects of Milk Amazake on Skin Elasticity, Hydration, and Transepidermal Water Loss: An 8-Week Double-Blind, Randomized, Controlled Trial (2023)

Low-molecular-weight collagen peptides supplement promotes a healthy skin: A randomized, double-blinded, placebo-controlled study (2023)

Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study (2023)

Impact of defensins-containing body cream on skin composition (2023)

Double-blind, Randomized Trial on the Effectiveness of Acetylhexapeptide-3 Cream and Palmitoyl Pentapeptide-4 Cream for Crow's Feet (2023)

Protective effects of a day/night dual-antioxidant serum on skin: A randomized, regimen-controlled study in Chinese women exposed to air pollution (2023)

Whitening effect of kojic acid dipalmitate loaded nanosized ethosomal gel for the treatment of hyperpigmentation: In vitro and in vivo characterization (2022)

Efficacy Evaluation of a Cosmetic Product for the Periocular Area in Caucasian Women Aged Over 40 Years Old (2022)

Oral Supplementation of Low-Molecular-Weight Collagen Peptides Reduces Skin Wrinkles and Improves Biophysical Properties of Skin: A Randomized, Double-Blinded, Placebo-Controlled Study (2022)

An open-label, 4-week, prospective clinical study evaluating the efficacy and safety of a novel targeted skin care line addressing five common skin conditions (2022)

Efficacy and tolerability of a novel skin cream for improving periocular rhytids and dryness (2022)

Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs (2022)

Effect of green tea extract loaded chitosan microparticles on facial skin: A split-face, double-blind, randomized placebo-controlled study (2022)

An Open-Label Clinical Trial Analyzing the Efficacy of a Novel Telomere-Protecting Antiaging Face Cream (2022)

Effect of Rice ( Oryza sativa L.) Ceramides Supplementation on Improving Skin Barrier Functions and Depigmentation: An Open-Label Prospective Study (2022)

Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide (2022)

A dermocosmetic formulation containing Vichy volcanic mineralizing water, Vitreoscilla filiformis extract, niacinamide, hyaluronic acid, and vitamin E regenerates and repairs acutely stressed skin (2022)

Effect of a Topical Collagen Tripeptide on Antiaging and Inhibition of Glycation of the Skin: A Pilot Study (2022)

Oral intake of a new full-spectrum hyaluronan improves skin profilometry and ageing: a randomized, double-blind, placebo-controlled clinical trial (2021)

Prospective, Randomized, Comparative Study of the Cutaneous Effects of a Topical Body Treatment Compared to a Bland Moisturizer (2021)

Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study (2021)

Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study (2021)

A Randomized, Double-Blind, Split-Body, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Tolerability of a Topical Body Firming Moisturizer for Upper Arm Rejuvenation (2021)

Oral Pycnogenol® Intake Benefits the Skin in Urban Chinese Outdoor Workers: A Randomized, Placebo-Controlled, Double-Blind, and Crossover Intervention Study (2021)

A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity (2021)

Efficacy and Tolerability of a Novel Topical Treatment for Neck: A Randomized, Double-blind, Regimen-Controlled Study (2021)

Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers (2021)

Night Cream Containing Melatonin, Carnosine and Helichrysum italicum Extract Helps Reduce Skin Reactivity and Signs of Photodamage: Ex Vivo and Clinical Studies (2020)

Skin scars and wrinkles temporary camouflage in dermatology and oncoesthetics: focus on acetyl hexapeptide-8 (2020)

Effect of defensins-containing eye cream on periocular rhytids and skin quality (2020)

Amazake made from sake cake and rice koji suppresses sebum content in differentiated hamster sebocytes and improves skin properties in humans (2020)

Efficacy of a Dermocosmetic Serum Combining Bakuchiol and Vanilla Tahitensis Extract to Prevent Skin Photoaging in vitro and to Improve Clinical Outcomes for Naturally Aged Skin (2020)

A Dermonutrient Containing Special Collagen Peptides Improves Skin Structure and Function: A Randomized, Placebo-Controlled, Triple-Blind Trial Using Confocal Laser Scanning Microscopy on the Cosmetic Effects and Tolerance of a Drinkable Collagen Supplement (2020)

An Open-Label Single-Arm, Monocentric Study Assessing the Efficacy and Safety of Natural Pterostilbene (Pterocarpus marsupium) for Skin Brightening and Antiaging Effects (2020)

A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study (2019)

Novel Hydrolyzed Chicken Sternal Cartilage Extract Improves Facial Epidermis and Connective Tissue in Healthy Adult Females: A Randomized, Double-Blind, Placebo-Controlled Trial (2019)

Combinatorial application of dissolving microneedle patch and cream for improvement of skin wrinkles, dermal density, elasticity, and hydration (2019)

A single-center clinical trial to evaluate the efficacy of a tripeptide/hexapeptide antiaging regimen (2019)

Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration (2018)

Multi-Center, Double-Blind, Vehicle-Controlled Clinical Trial of an Alpha and Beta Defensin-Containing Anti-Aging Skin Care Regimen With Clinical, Histopathologic, Immunohistochemical, Photographic, and Ultrasound Evaluation (2018)

Efficacy and safety of a novel, soluble microneedle patch for the improvement of facial wrinkle (2018)

Redefining face contour with a novel anti-aging cosmetic product: an open-label, prospective clinical study (2017)

Hyaluronic acid microneedle patch for the improvement of crow's feet wrinkles (2017)

Ingestion of an Oral Hyaluronan Solution Improves Skin Hydration, Wrinkle Reduction, Elasticity, and Skin Roughness: Results of a Clinical Study (2017)

Effects of Dietary Supplementation with Fish Scales-Derived Collagen Peptides on Skin Parameters and Condition: A Randomized, Placebo-Controlled, Double-Blind Study (2017)

Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period (2017)

An Insight into the Changes in Skin Texture and Properties following Dietary Intervention with a Nutricosmeceutical Containing a Blend of Collagen Bioactive Peptides and Antioxidants (2017)

The effect of dietary intake of coenzyme Q10 on skin parameters and condition: Results of a randomised, placebo-controlled, double-blind study (2017)

Clinical effects of an oral supplement rich in antioxidants on skin radiance in women (2016)

Preliminary study on the development of an antistretch marks water-in-oil cream: ultrasound assessment, texture analysis, and sensory analysis (2016)

Ingestion of bioactive collagen hydrolysates enhance facial skin moisture and elasticity and reduce facial ageing signs in a randomised double-blind placebo-controlled clinical study (2016)

Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo (2016)

Biological effects of rutin on skin aging (2016)

A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females (2016)

In vitro and clinical evaluation of SIG1273: a cosmetic functional ingredient with a broad spectrum of anti-aging and antioxidant activities (2016)

Assessment of a Novel Anti-Aging Hand Cream (2016)

Elastin hydrolysate derived from fish enhances proliferation of human skin fibroblasts and elastin synthesis in human skin fibroblasts and improves the skin conditions (2016)

A placebo-controlled, double-blind clinical trial to evaluate the efficacy of Imedeen Time Perfection for improving the appearance of photodamaged skin (2016)

Biorevitalizing effect of a novel facial serum containing apple stem cell extract, pro-collagen lipopeptide, creatine, and urea on skin aging signs (2016)

Superior Efficacy of an Herbal-based Cosmeceutical Compared With Common Prescription and Cosmetic Antiaging Therapies (2016)

Randomized, double-blinded, vehicle-controlled, split-face study to evaluate the effects of topical application of a Gold Silk Sericin/Niacinamide/Signaline complex on biophysical parameters related to skin ageing (2015)

Acetyl hexapeptide-3 in a cosmetic formulation acts on skin mechanical properties - clinical study (2015)

The Potential Role of Topically Applied Heparan Sulfate in the Treatment of Photodamage (2015)

Assessment of the safety and efficacy of topical copper chlorophyllin in women with photodamaged facial skin (2015)

A dietary supplement improves facial photoaging and skin sebum, hydration and tonicity modulating serum fibronectin, neutrophil elastase 2, hyaluronic acid and carbonylated proteins (2015)

One-year topical stabilized retinol treatment improves photodamaged skin in a double-blind, vehicle-controlled trial (2015)

A double-blind randomized study comparing the association of Retinol and LR2412 with tretinoin 0.025% in photoaged skin (2015)

Clinical effects of ingesting collagen hydrolysate on facial skin properties: A randomized, placebo-controlled, double-blind trial (2015)

Evaluation of the clinical efficacy and safety of an eye counter pad containing caffeine and vitamin K in emulsified Emu oil base (2015)

Evaluation of a novel anti-aging topical formulation containing cycloastragenol, growth factors, peptides, and antioxidants (2014)

A single center, pilot, double-blinded, randomized, comparative, prospective clinical study to evaluate improvements in the structure and function of facial skin with tazarotene 0.1% cream alone and in combination with GliSODin(®) Skin Nutrients Advanced Anti-Aging Formula (2014)

A novel, volumizing cosmetic formulation significantly improves the appearance of target Glabellar lines, nasolabial folds, and crow's feet in a double-blind, vehicle-controlled clinical trial (2014)

Long-term topical oestrogen treatment of sun-exposed facial skin in post-menopausal women does not improve facial wrinkles or skin elasticity, but induces matrix metalloproteinase-1 expression (2014)

A double-blind controlled clinical trial assessing the effect of topical gels on striae distensae (stretch marks): a non-invasive imaging, morphological and immunohistochemical study (2013)

Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study (2013)

The use of green tea extract in cosmetic formulations: not only an antioxidant active ingredient (2013)

Application of tetra-isopalmitoyl ascorbic acid in cosmetic formulations: stability studies and in vivo efficacy (2012)

The effects of natural S-equol supplementation on skin aging in postmenopausal women: a pilot randomized placebo-controlled trial (2012)

Pycnogenol® effects on skin elasticity and hydration coincide with increased gene expressions of collagen type I and hyaluronic acid synthase in women (2012)

Dermal penetration of creatine from a face-care formulation containing creatine, guarana and glycerol is linked to effective antiwrinkle and antisagging efficacy in male subjects (2011)

Changes in skin mechanical properties after long-term application of cream containing green tea extract (2011)

Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment (2011)

Calendula extract: effects on mechanical parameters of human skin (2011)

Retinyl retinoate, a novel hybrid vitamin derivative, improves photoaged skin: a double-blind, randomized-controlled trial (2011)

Skin moisturizing effects of panthenol-based formulations (2011)

Retinaldehyde/hyaluronic acid fragments: a synergistic association for the management of skin aging (2011)

Folic acid and creatine improve the firmness of human skin in vivo (2011)

An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging (2010)

Combination of physiologically balanced growth factors with antioxidants for reversal of facial photodamage (2010)

In vivo skin effects of a dimethylaminoethanol (DMAE) based formulation (2009)

Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin (2008)

In vitro antioxidant activity and in vivo efficacy of topical formulations containing vitamin C and its derivatives studied by non-invasive methods (2008)

Clinical, histologic, and ultrastructural changes after use of human growth factor and cytokine skin cream for the treatment of skin rejuvenation (2008)

A new decorin-like tetrapeptide for optimal organization of collagen fibres (2008)

A novel treatment option for photoaged skin (2008)

Antiaging Effects of Topical Lactobionic Acid: Results of A Controlled Usage Study (2008)

The clinical anti-aging effects of topical kinetin and niacinamide in Asians: a randomized, double-blind, placebo-controlled, split-face comparative trial (2007)

Topical manganese peptide in the treatment of photodamaged skin (2007)

Effect of myristyl nicotinate on retinoic acid therapy for facial photodamage (2007)

In vivo assessment of Ectoin: a randomized, vehicle-controlled clinical trial (2007)

Effect of a novel dietary supplement on skin aging in post-menopausal women (2006)

Effects and side-effects of 2% progesterone cream on the skin of peri- and postmenopausal women: results from a double-blind, vehicle-controlled, randomized study (2005)

Niacinamide: A B vitamin that improves aging facial skin appearance (2005)

Topical application of Bifidobacterium-fermented soy milk extract containing genistein and daidzein improves rheological and physiological properties of skin (2004)

Supplementation with Evelle improves skin smoothness and elasticity in a double-blind, placebo-controlled study with 62 women (2004)

The use of polyhydroxy acids (PHAs) in photoaged skin (2004)

Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo (2003)

Split face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gel (2002)

A randomized, placebo-controlled trial of topical retinol in the treatment of cellulite (2000)

Use of topical ascorbic acid and its effects on photodamaged skin topography (1999)

Efficacy of topical 0.05% retinaldehyde in skin aging by ultrasound and rheological techniques (1999)

A clinicopathological study of the effects of topical retinyl propionate cream in skin photoageing (1998)

Treatment of skin aging with topical estrogens (1996)

Treatment of skin ageing symptoms in perimenopausal females with estrogen compounds. A pilot study (1994)

Tretinoin emollient cream 0.01% for the treatment of photoaged skin (1993)

An oral approach to the treatment of photodamaged skin: a pilot study (1992)

Natural cartilage polysaccharides for the treatment of sun-damaged skin in females: a double-blind comparison of Vivida and Imedeen (1992)

Tretinoin emollient cream: a new therapy for photodamaged skin (1992)

Topical tretinoin for treatment of photodamaged skin. A multicenter study (1991)

Imedeen for the treatment of degenerated skin in females (1991)

Treatment of photodamaged facial skin with topical tretinoin (1989)