Skin Barrier Function

A Multi-Center, Double-Blind, Randomized, Comparator Controlled Trial Evaluating Topical Formulations for Skin Fragility of the Arms (2024)

A Novel Protection and Repair Skincare Regimen Shows Efficacy for Improving Environmental Skin Aging (2024)

Open-label topical application of tetrahexyldecyl ascorbate and acetyl zingerone containing serum improves the appearance of photoaging and uneven pigmentation (2024)

Derivatives of L-Ascorbic Acid in Emulgel: Development and Comprehensive Evaluation of the Topical Delivery System (2023)

Effects of Milk Amazake on Skin Elasticity, Hydration, and Transepidermal Water Loss: An 8-Week Double-Blind, Randomized, Controlled Trial (2023)

Impact of defensins-containing body cream on skin composition (2023)

Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study (2023)

Double-blind, Randomized Trial on the Effectiveness of Acetylhexapeptide-3 Cream and Palmitoyl Pentapeptide-4 Cream for Crow's Feet (2023)

Cosmetic Formulations with Melaleuca alternifolia Essential Oil for the Improvement of Photoaged Skin: A Double-Blind, Randomized, Placebo-Controlled Clinical Study (2023)

Protective effects of a day/night dual-antioxidant serum on skin: A randomized, regimen-controlled study in Chinese women exposed to air pollution (2023)

An open-label, 4-week, prospective clinical study evaluating the efficacy and safety of a novel targeted skin care line addressing five common skin conditions (2022)

Effect of green tea extract loaded chitosan microparticles on facial skin: A split-face, double-blind, randomized placebo-controlled study (2022)

Koji amazake Maintains Water Content in the Left Cheek Skin of Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Comparative Trial (2022)

Effect of Rice ( Oryza sativa L.) Ceramides Supplementation on Improving Skin Barrier Functions and Depigmentation: An Open-Label Prospective Study (2022)

Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer (2022)

Safety and efficacy of combined essential oils for the skin barrier properties: In vitro, ex vivo and clinical studies (2022)

Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide (2022)

A dermocosmetic formulation containing Vichy volcanic mineralizing water, Vitreoscilla filiformis extract, niacinamide, hyaluronic acid, and vitamin E regenerates and repairs acutely stressed skin (2022)

Oral intake of a new full-spectrum hyaluronan improves skin profilometry and ageing: a randomized, double-blind, placebo-controlled clinical trial (2021)

Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial (2021)

Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study (2021)

Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study (2021)

Oral Pycnogenol® Intake Benefits the Skin in Urban Chinese Outdoor Workers: A Randomized, Placebo-Controlled, Double-Blind, and Crossover Intervention Study (2021)

Clinical Evaluation of a Nature-Based Bakuchiol Anti-Aging Moisturizer for Sensitive Skin (2020)

Night Cream Containing Melatonin, Carnosine and Helichrysum italicum Extract Helps Reduce Skin Reactivity and Signs of Photodamage: Ex Vivo and Clinical Studies (2020)

Amazake made from sake cake and rice koji suppresses sebum content in differentiated hamster sebocytes and improves skin properties in humans (2020)

Effects of Skin Lightening Cream Agents - Hydroquinone and Kojic Acid, on the Skin of Adult Female Experimental Rats (2020)

A 10% Lactobionic acid-containing moisturizer reduces skin surface pH without irritation-An in vivo/in vitro study (2019)

Novel Hydrolyzed Chicken Sternal Cartilage Extract Improves Facial Epidermis and Connective Tissue in Healthy Adult Females: A Randomized, Double-Blind, Placebo-Controlled Trial (2019)

Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days (2019)

Evaluation of the safety and efficacy of a triple combination cream (hydroquinone, tretinoin, and fluocinolone) for treatment of melasma in Middle Eastern skin (2019)

A single-center clinical trial to evaluate the efficacy of a tripeptide/hexapeptide antiaging regimen (2019)

Multi-Center, Double-Blind, Vehicle-Controlled Clinical Trial of an Alpha and Beta Defensin-Containing Anti-Aging Skin Care Regimen With Clinical, Histopathologic, Immunohistochemical, Photographic, and Ultrasound Evaluation (2018)

Efficacy and safety of a novel, soluble microneedle patch for the improvement of facial wrinkle (2018)

Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques (2017)

The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study (2017)

A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora (2017)

A multicenter, placebo-controlled, double-blind clinical trial assessing the effects of a multicomponent nutritional supplement for treating photoaged skin in healthy women (2017)

Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo (2016)

A Randomized, Double-blind, Placebo-controlled Clinical Trial Evaluating an Oral Anti-aging Skin Care Supplement for Treating Photodamaged Skin (2016)

A placebo-controlled, double-blind clinical trial to evaluate the efficacy of Imedeen Time Perfection for improving the appearance of photodamaged skin (2016)

Randomized, double-blinded, vehicle-controlled, split-face study to evaluate the effects of topical application of a Gold Silk Sericin/Niacinamide/Signaline complex on biophysical parameters related to skin ageing (2015)

The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials (2015)

The Potential Role of Topically Applied Heparan Sulfate in the Treatment of Photodamage (2015)

Design, characterization, and clinical evaluation of argan oil nanostructured lipid carriers to improve skin hydration (2014)

Does Argan oil have a moisturizing effect on the skin of postmenopausal women? (2013)

Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study (2013)

The use of green tea extract in cosmetic formulations: not only an antioxidant active ingredient (2013)

Efficacy of a novel treatment serum in the improvement of photodamaged skin (2013)

Effect of olive and sunflower seed oil on the adult skin barrier: implications for neonatal skin care (2013)

Influence of niacinamide containing formulations on the molecular and biophysical properties of the stratum corneum (2013)

Application of tetra-isopalmitoyl ascorbic acid in cosmetic formulations: stability studies and in vivo efficacy (2012)

In vivo investigations on the penetration of various oils and their influence on the skin barrier (2012)

The effects of natural S-equol supplementation on skin aging in postmenopausal women: a pilot randomized placebo-controlled trial (2012)

Clinical efficacy of adapalene (differin(®)) 0.3% gel in Chilean women with cutaneous photoaging (2012)

Skin moisturizing effects of panthenol-based formulations (2011)

Instrumental analysis of the pattern of improvement and that of recurrence of melasma in Thai females treated with Kligman-Willis triple combination therapy: confirmation by using its two different formulae (2011)

Supplementation of flaxseed oil diminishes skin sensitivity and improves skin barrier function and condition (2011)

Retinyl retinoate induces hyaluronan production and less irritation than other retinoids (2010)

A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0.02% tretinoin product regimen (2010)

Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid (2010)

Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes (2010)

Glycylglycine decreases the size of conspicuous facial pores: Single-blinded half areas of face-applied study (2009)

In vitro antioxidant activity and in vivo efficacy of topical formulations containing vitamin C and its derivatives studied by non-invasive methods (2008)

A double-blind, randomized clinical trial evaluating the dermatologic benefits of coffee berry extract (2008)

Effect of myristyl nicotinate on retinoic acid therapy for facial photodamage (2007)

A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin (2007)

Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques (2006)

Facilitating facial retinization through barrier improvement (2006)

'Keratolytic' properties of benzoyl peroxide and retinoic acid resemble salicylic acid in man (2006)

Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea (2005)

Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin (2005)

Moisturizing effects of topical nicotinamide on atopic dry skin (2005)

Vehicle-controlled effect of urea on normal and SLS-irritated skin (2004)

Dexpanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritation (2002)

Clinical study of safety and efficacy of using topical kinetin 0.1% (Kinerase®) to treat photodamaged skin (2002)

Do urea/ammonium lactate combinations achieve better skin protection and hydration than either component alone? (2002)

The influence of a cream containing 20% glycerin and its vehicle on skin barrier properties (2001)

The effects of topical alpha-hydroxyacids on the normal skin barrier of hairless mice (2001)

Photodamage pilot study: a double-blind, vehicle-controlled study to assess the efficacy and safety of tazarotene 0.1% gel (2000)

Effect of topically applied dexpanthenol on epidermal barrier function and stratum corneum hydration. Results of a human in vivo study (2000)

Glycerol accelerates recovery of barrier function in vivo (1999)

Tolerance profile of retinol, retinaldehyde and retinoic acid under maximized and long-term clinical conditions (1999)

Imedeen in the treatment of photoaged skin: an efficacy and safety trial over 12 months (1998)

Alpha hydroxyacids modulate stratum corneum barrier function (1997)

Mechanism of action of a lipophilic derivative of salicylic acid on normal skin (1995)

Effects of petrolatum on stratum corneum structure and function (1992)

Hydration of the stratum corneum (1986)