Rutin

Introduction

What is rutin?

Rutin is a natural compound found in apples, passion flowers, buckwheat, tea and the plant Ruta graveolens, from which it derives its name. It consists of the flavonol quercetin and the sugar rutinose (R).

Is rutin stable?

Rutin is sensitive to light and degrades when exposed to UV radiation, but it can be stabilised when encapsulated into ethosomes (R).

Does rutin get absorbed?

Rutin has poor skin permeation because of its inability to overcome the skin barrier. However, it can be delivered to the deeper skin layers when loaded onto ethosomes (R) or formulated as a nanocrystal gel (R).

Efficacy
Outcome Grade Effect Studies
Skin Elasticity
B
  • ๐Ÿ ฉ๐Ÿ ฉ๐Ÿ ฉ
Wrinkles
B
  • ๐Ÿ ซ๐Ÿ ซ๐Ÿ ซ
Skin Density
B
  • ๐Ÿ ฉ๐Ÿ ฉ
Mechanisms
Outcome Grade Effect Studies
Collagen
C
  • ๐Ÿ ฉ๐Ÿ ฉ๐Ÿ ฉ
Cellular Senescence
C
  • ๐Ÿ ซ๐Ÿ ซ๐Ÿ ซ
Collagenase
C
  • ๐Ÿ ซ๐Ÿ ซ๐Ÿ ซ
Reactive Species
C
  • ๐Ÿ ซ๐Ÿ ซ๐Ÿ ซ
Cell Viability
D
  • โ‡งโ‡ฉ
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