Reactive Species

Ingredients

Show 21 more ingredients
Ingredient	Grade	Effect	Evidence	Studies
Rutin	C	🠫🠫🠫 Marked	★★ Some	1 study 6 participants
Alpha-Tocopherol	C	🠫 Slight	★★ Some	4 studies 3 participants
Green Tea Extract	C	🠫 Slight	★★ Some	2 studies 6 participants
Resveratrol	C	🠫 Slight	★★ Some	2 studies 6 participants
Coenzyme Q10	C	⇩ Potential	★★ Some	2 studies 19 participants
Ascorbic Acid	D	🠫🠫🠫 Marked	★ Basic	5 studies
Ascorbyl Palmitate	D	🠫🠫🠫 Marked	★ Basic	3 studies
Glutathione	D	🠫🠫🠫 Marked	★ Basic	1 study
Kojic Dipalmitate + Rosehip Oil	D	🠫 Slight	★ Basic	1 study
Lotus Extract	D	🠫 Slight	★ Basic	1 study
Retinol	D	🠫 Slight	★ Basic	1 study
Retinyl Ascorbate	D	🠫 Slight	★ Basic	1 study
Tretinoin	D	🠫 Slight	★ Basic	1 study
Rhamnose-Rich Polysaccharides	D	🠫 Slight	★ Basic	1 study
Kojic Dipalmitate	D	🠫 Slight	★ Basic	1 study
Rosehip Oil	D	🠫 Slight	★ Basic	1 study
Butylated Hydroxylanisol	D	🠫 Slight	★ Basic	1 study
Ascorbyl Glucoside	D	🠫 Slight	★ Basic	1 study
Alpha-Lipoic Acid	D	⇩ Potential	★ Basic	2 studies
DMAE	D	⇩ Potential	★ Basic	1 study
SIG-1273	D	⇩ Potential	★ Basic	1 study
Ascorbyl Tetraisopalmitate	E	– No Effect	★★ Some	1 study 3 participants
Magnesium Ascorbyl Phosphate	E	– No Effect	★ Basic	1 study
Alpha-Tocopherol Acetate	E	– No Effect	★ Basic	1 study
Retinyl Palmitate	E	– No Effect	★ Basic	1 study
Ascorbyl Dipalmitate	E	– No Effect	★ Basic	1 study

Products

Product	Grade	Effect	Evidence	Studies
SkinBetter Alto Defense Serum	D	🠫🠫🠫 Marked	★ Basic	2 studies
Ever Collagen Corrector Collagen Tripeptide Ampoule	D	🠫🠫🠫 Marked	★ Basic	1 study
ISDIN Ureadin Fusion Anti-Wrinkle Serum Lift	D	🠫🠫🠫 Marked	★ Basic	1 study

Supplements

Supplement				Grade		Effect		Evidence		Studies
Green Tea				C		🠫 Slight		★★ Some		1 study 32 participants

Treatments

Coming soon.

Skincare treatments can penetrate more deeply into the skin to provide faster, more dramatic and longer-lasting results than topical products, but they are also much more expensive.

Review all of the scientific evidence before spending thousands of dollars on treatments that won't work, or that make your skin worse due to the side effects.

Latest Research

Reactive Species

Coming soon.

Comparative Studies on the Photoreactivity, Efficacy, and Safety of Depigmenting Agents (2023)

Nanoemulsion Containing Kojic Dipalmitate and Rosehip Oil: A Promising Formulation to Treat Melasma (2023)

Effect of a Topical Collagen Tripeptide on Antiaging and Inhibition of Glycation of the Skin: A Pilot Study (2022)

A comprehensive topical antioxidant inhibits oxidative stress induced by blue light exposure and cigarette smoke in human skin tissue (2021)

Protective effects of a comprehensive topical antioxidant against ozone-induced damage in a reconstructed human skin model (2021)

Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques (2017)

A Randomized Controlled Trial of Green Tea Beverages on the in vivo Radical Scavenging Activity in Human Skin (2017)

Biological effects of rutin on skin aging (2016)

In vitro and clinical evaluation of SIG1273: a cosmetic functional ingredient with a broad spectrum of anti-aging and antioxidant activities (2016)

Biorevitalizing effect of a novel facial serum containing apple stem cell extract, pro-collagen lipopeptide, creatine, and urea on skin aging signs (2016)

Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects (2015)

Tannase-converted green tea catechins and their anti-wrinkle activity in humans (2013)

Evaluation of the antioxidative capability of commonly used antioxidants in dermocosmetics by in vivo detection of protein carbonylation in human stratum corneum (2012)

New insights on dimethylaminoethanol (DMAE) features as a free radical scavenger (2012)

Nelumbo nucifera extracts as whitening and anti-wrinkle cosmetic agent (2011)

Pharmacological properties of rhamnose-rich polysaccharides, potential interest in age-dependent alterations of connectives tissues (2006)

Topical delivery of retinyl ascorbate: 4. Comparative anti-oxidant activity towards DPPH (2005)

High global antioxidant protection and stimulation of the collagen synthesis of new anti-aging product containing an optimized active mix (2002)

Radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl of ascorbic acid 2-glucoside (AA-2G) and 6-acyl-AA-2G (2001)