Skin Density

Ingredients

Show 6 more ingredients
Ingredient	Grade	Effect	Evidence	Studies
Apigenin	B	🠩🠩🠩 Marked	★★★ Fair	1 study 40 participants
Rutin	B	🠩🠩 Notable	★★★ Fair	1 study 40 participants
Lactic Acid + Tretinoin	B	🠩 Slight	★★★ Fair	1 study 25 participants
Retinol	B	🠩 Slight	★★★ Fair	1 study 19 participants
Adenosine	C	⇧ Potential	★★★ Fair	2 studies 43 participants
Salicin	C	⇧ Potential	★★ Some	1 study 29 participants
Hydroquinone + Tretinoin + Corticosteroid	C	⇧ Potential	★★ Some	1 study 17 participants
Alpha-Lipoic Acid	C	⇧ Potential	★★ Some	1 study 12 participants
Rice Peptides	E	– No Effect	★★★ Fair	1 study 30 participants
Ascorbyl Tetraisopalmitate	E	– No Effect	★★★ Fair	1 study 30 participants
Ascorbyl Tetraisopalmitate + Rice Peptides	E	– No Effect	★★★ Fair	1 study 30 participants

Products

Product	Grade	Effect	Evidence	Studies
NeoStrata Skin Active Line Lift	B	🠩 Slight	★★★ Fair	1 study 70 participants
Revision Skincare BodiFirm	B	🠩 Slight	★★★ Fair	1 study 40 participants
ISDIN Ureadin Fusion Anti-Wrinkle Serum Lift	C	⇧ Potential	★★ Some	1 study 32 participants
Ever Collagen Corrector Collagen Tripeptide Ampoule	C	⇧ Potential	★★ Some	1 study 22 participants
SkinMedica Firm & Tone Lotion for Body	E	– No Effect	★★★ Fair	1 study 54 participants

Supplements

Show 7 more supplements
Supplement	Grade	Effect	Evidence	Studies
Imedeen Prime Renewal	B	🠩🠩🠩 Marked	★★★ Fair	1 study 80 participants
Cartilage Supplement	B	🠩🠩🠩 Marked	★★★ Fair	1 study 43 participants
Cartidyss	B	🠩🠩🠩 Marked	★★★ Fair	1 study 43 participants
Collagen Supplement	B	🠩 Slight	★★★ Fair	1 study 97 participants
Verisol	B	🠩 Slight	★★★ Fair	1 study 97 participants
Elasten	C	🠩🠩 Notable	★★ Some	1 study 72 participants
Imedeen	C	⇧ Potential	★★ Some	1 study 111 participants
Imedeen Man-Age-Ment	C	⇧ Potential	★★ Some	1 study 41 participants
Imedeen Time Perfection	D	⇧ Potential	★ Basic	2 studies 244 participants
Imedeen Derma One	E	– No Effect	★★★ Fair	1 study 146 participants
Coenzyme Q10 Supplement	E	– No Effect	★★★★ Good	1 study 32 participants
Q10Vital	E	– No Effect	★★★★ Good	1 study 32 participants

Treatments

Coming soon.

Skincare treatments can penetrate more deeply into the skin to provide faster, more dramatic and longer-lasting results than topical products, but they are also much more expensive.

Review all of the scientific evidence before spending thousands of dollars on treatments that won't work, or that make your skin worse due to the side effects.

Latest Research

Coming soon.

Restoration of Aging Body Skin: Evidence-Based Development of a Topical Formulation for Improving Body Skin Quality (2023)

Effect of a Topical Collagen Tripeptide on Antiaging and Inhibition of Glycation of the Skin: A Pilot Study (2022)

Oral Supplementation with Hydrolyzed Fish Cartilage Improves the Morphological and Structural Characteristics of the Skin: A Double-Blind, Placebo-Controlled Clinical Study (2021)

Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study (2021)

A Randomized, Double-Blind, Split-Body, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Tolerability of a Topical Body Firming Moisturizer for Upper Arm Rejuvenation (2021)

A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study (2019)

Combinatorial application of dissolving microneedle patch and cream for improvement of skin wrinkles, dermal density, elasticity, and hydration (2019)

Evaluation of the safety and efficacy of a triple combination cream (hydroquinone, tretinoin, and fluocinolone) for treatment of melasma in Middle Eastern skin (2019)

Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration (2018)

A multicenter, placebo-controlled, double-blind clinical trial assessing the effects of a multicomponent nutritional supplement for treating photoaged skin in healthy women (2017)

The effect of dietary intake of coenzyme Q10 on skin parameters and condition: Results of a randomised, placebo-controlled, double-blind study (2017)

Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo (2016)

Biological effects of rutin on skin aging (2016)

A Randomized, Double-blind, Placebo-controlled Clinical Trial Evaluating an Oral Anti-aging Skin Care Supplement for Treating Photodamaged Skin (2016)

A placebo-controlled, double-blind clinical trial to evaluate the efficacy of Imedeen Time Perfection for improving the appearance of photodamaged skin (2016)

Biorevitalizing effect of a novel facial serum containing apple stem cell extract, pro-collagen lipopeptide, creatine, and urea on skin aging signs (2016)

Superior Efficacy of an Herbal-based Cosmeceutical Compared With Common Prescription and Cosmetic Antiaging Therapies (2016)

Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology (2015)

Assessment of clinical effects and safety of an oral supplement based on marine protein, vitamin C, grape seed extract, zinc, and tomato extract in the improvement of visible signs of skin aging in men (2015)

The clinical efficacy of cosmeceutical application of liquid crystalline nanostructured dispersions of alpha lipoic acid as anti-wrinkle (2014)

A novel, volumizing cosmetic formulation significantly improves the appearance of target Glabellar lines, nasolabial folds, and crow's feet in a double-blind, vehicle-controlled clinical trial (2014)

An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging (2010)

Effect of a novel dietary supplement on skin aging in post-menopausal women (2006)

Topical retinol improves cellulite (1998)

Imedeen in the treatment of photoaged skin: an efficacy and safety trial over 12 months (1998)