Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial

Study Design

Subject Type

Human

Trial Design

Single-Blind, Randomised, Controlled

Trial Duration

84 days

Participants

92 (90 completed)

Efficacy

Intervention(s)			Outcome		Method		Effect	Description
Thiamidol			Melasma		Clinical grading		🠫	Sign in to read for free
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Hyaluronic Acid			Melasma		Clinical grading		🠫	Sign in to read for free
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Eucerin UltraWHITE Spotless Double Booster Serum Hyaluronic Acid + Thiamidol			Melasma		Clinical grading		🠫	Sign in to read for free
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Hyaluronic Acid			Skin Barrier Function		Tewameter		–	Sign in to read for free
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Eucerin UltraWHITE Spotless Double Booster Serum Hyaluronic Acid + Thiamidol			Skin Barrier Function		Tewameter		–	Sign in to read for free
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Thiamidol			Skin Barrier Function		Tewameter		–	Sign in to read for free
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Mechanisms

Intervention(s)			Outcome		Method		Effect	Description
Eucerin UltraWHITE Spotless Double Booster Serum Hyaluronic Acid + Thiamidol			Melanin		Antera3D		–	Sign in to read for free
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Thiamidol			Melanin		Antera3D		–	Sign in to read for free
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Hyaluronic Acid			Melanin		Antera3D		🠩	Sign in to read for free
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Side Effects

Intervention(s)			Outcome		Effect	Description
Eucerin UltraWHITE Spotless Double Booster Serum Hyaluronic Acid + Thiamidol			Itching		⇧	Sign in to read for free
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Hyaluronic Acid			Itching		⇧	Sign in to read for free
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Thiamidol			Itching		–	Sign in to read for free
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Thiamidol			Skin Discomfort		⇧	Sign in to read for free
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Hyaluronic Acid			Skin Discomfort		–	Sign in to read for free
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Eucerin UltraWHITE Spotless Double Booster Serum Hyaluronic Acid + Thiamidol			Skin Discomfort		⇧	Sign in to read for free
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Thiamidol			Skin Redness		⇧	Sign in to read for free
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Hyaluronic Acid			Skin Redness		⇧	Sign in to read for free
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Eucerin UltraWHITE Spotless Double Booster Serum Hyaluronic Acid + Thiamidol			Skin Redness		–	Sign in to read for free
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Study Summary

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