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Improvement of naturally aged skin with vitamin A (retinol)
Study Design
Subject Type
Human
Trial Design
Double-Blind, Randomised, Controlled
Trial Duration
168 days
Participants
36 (23 completed)
Age Range
80-96 years
Efficacy
Intervention(s)
Outcome
Method
Effect
Description
Retinol
Skin Smoothness
Clinical grading
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Retinol
Wrinkles
Clinical grading
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Mechanisms
Intervention(s)
Outcome
Method
Effect
Description
Retinol
CRABP2
RT-PCR
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Tretinoin
CRABP2
RT-PCR
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Retinol
Collagen
Immunostaining
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Retinol
Glycosaminoglycans
Immunohistologic and Western blot analyses
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Side Effects
Intervention(s)
Outcome
Effect
Description
Retinol
Itching
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Retinol
Peeling
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Retinol
Skin Discomfort
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Retinol
Skin Hydration
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Retinol
Skin Redness
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Study Summary
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