Effective Tyrosinase Inhibition by Thiamidol Results in Significant Improvement of Mild to Moderate Melasma

Efficacy

Intervention(s)		Outcome		Effect	Description
Hydroquinone		Hyperpigmentation		No Effect	Login to read descriptions for free
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Thiamidol		Hyperpigmentation		Decrease	Login to read descriptions for free
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Hydroquinone		Melasma		Decrease	Login to read descriptions for free
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Thiamidol		Melasma		Decrease	Login to read descriptions for free
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Side Effects

Intervention(s)		Outcome	Effect	Description
Thiamidol		Itching	Increase	Login to read descriptions for free
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Hydroquinone		Itching	Increase	Login to read descriptions for free
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Hydroquinone		Pain	No Effect	Login to read descriptions for free
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Thiamidol		Pain	No Effect	Login to read descriptions for free
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Thiamidol		Skin Redness	No Effect	Login to read descriptions for free
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Hydroquinone		Skin Redness	No Effect	Login to read descriptions for free
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Thiamidol		Swelling	No Effect	Login to read descriptions for free
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Hydroquinone		Swelling	No Effect	Login to read descriptions for free
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Study Design

Subject Type

Human

Trial Design

Double-Blind, Randomised, Controlled

Trial Duration

84 days

Participants

80 (59 completed)

Age Range

29-65 years

Study Summary

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