Tolerance profile of retinol, retinaldehyde and retinoic acid under maximized and long-term clinical conditions

Efficacy

Intervention(s)	Outcome	Effect	Description
Retinal	Skin Barrier Function	Potential Decrease	Login to read descriptions for free
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Retinol	Skin Barrier Function	Potential Decrease	Login to read descriptions for free
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Tretinoin	Skin Barrier Function	Potential Decrease	Login to read descriptions for free
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Side Effects

Intervention(s)	Outcome	Effect	Description
Tretinoin	Itching	Increase	Login to read descriptions for free
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Retinol	Itching	Increase	Login to read descriptions for free
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Retinal	Itching	No Effect	Login to read descriptions for free
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Retinol	Pain	Increase	Login to read descriptions for free
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Retinal	Pain	No Effect	Login to read descriptions for free
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Tretinoin	Pain	Increase	Login to read descriptions for free
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Retinol	Peeling	Increase	Login to read descriptions for free
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Tretinoin	Peeling	Increase	Login to read descriptions for free
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Retinal	Peeling	Increase	Login to read descriptions for free
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Retinal	Skin Redness	Increase	Login to read descriptions for free
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Retinol	Skin Redness	Increase	Login to read descriptions for free
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Tretinoin	Skin Redness	Increase	Login to read descriptions for free
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Study Design

Subject Type

Human

Trial Design

Double-Blind, Non-Randomised, Controlled

Trial Duration

308 days

Participants

355 (355 completed)

Study Summary