Tolerance profile of retinol, retinaldehyde and retinoic acid under maximized and long-term clinical conditions

Study Design

Subject Type

Human

Trial Design

Double-Blind, Controlled

Trial Duration

308 days

Participants

355 (355 completed)

Efficacy

Intervention(s)			Outcome		Method		Effect	Description
Retinol			Skin Barrier Function		Clinical grading		–	Sign in to read for free
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Retinal			Skin Barrier Function		Evaporimeter		–	Sign in to read for free
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Tretinoin			Skin Barrier Function		Evaporimeter		–	Sign in to read for free
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Side Effects

Intervention(s)			Outcome		Effect	Description
Tretinoin			Itching		⇧	Sign in to read for free
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Retinol			Itching		⇧	Sign in to read for free
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Retinal			Itching		–	Sign in to read for free
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Retinal			Peeling		⇧	Sign in to read for free
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Retinol			Peeling		⇧	Sign in to read for free
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Tretinoin			Peeling		⇧	Sign in to read for free
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Tretinoin			Skin Discomfort		⇧	Sign in to read for free
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Retinal			Skin Discomfort		–	Sign in to read for free
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Retinol			Skin Discomfort		⇧	Sign in to read for free
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Retinal			Skin Redness		⇧	Sign in to read for free
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Tretinoin			Skin Redness		⇧	Sign in to read for free
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Retinol			Skin Redness		⇧	Sign in to read for free
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Study Summary

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