4-Hexyl-1,3-phenylenediol, a nuclear factor-κB inhibitor, improves photodamaged skin and clinical signs of ageing in a double-blinded, randomized controlled trial

Study Design

Subject Type

Human

Trial Design

Double-Blind, Randomised, Controlled

Trial Duration

56 days

Participants

61 (59 completed)

Age Range

40-65 years

Efficacy

Intervention(s)			Outcome		Method		Effect	Description
Hexylresorcinol			Fine Lines		Clinical grading		🠫	Sign in to read for free
Sign in to read for free
Hexylresorcinol			Hyperpigmentation		Clinical grading		🠫	Sign in to read for free
Sign in to read for free
Hexylresorcinol			Skin Brightness		Clinical grading		🠩	Sign in to read for free
Sign in to read for free
Hexylresorcinol			Wrinkles		Clinical grading		🠫	Sign in to read for free
Sign in to read for free

Mechanisms

Intervention(s)			Outcome		Method		Effect	Description
Hexylresorcinol			Collagen		Quantitative PCR		⇧	Sign in to read for free
Sign in to read for free
Hexylresorcinol			Collagen		Quantitative PCR		🠩	Sign in to read for free
Sign in to read for free
Hexylresorcinol			Collagen		Quantitative PCR		🠩	Sign in to read for free
Sign in to read for free
Hexylresorcinol			Elastic Fibres		Quantitative PCR		⇧	Sign in to read for free
Sign in to read for free
Hexylresorcinol			Elastic Fibres		Quantitative PCR		🠩	Sign in to read for free
Sign in to read for free
Hexylresorcinol			Elastic Fibres		Quantitative PCR		🠩	Sign in to read for free
Sign in to read for free
Hexylresorcinol			NF-kB Activity		Assay		🠫	Sign in to read for free
Sign in to read for free

Study Summary

Sign in to read for free