Skin Brightness

Ingredients

Show 15 more ingredients
Ingredient	Grade	Effect	Evidence	Studies
Glycolic Acid	C	Slight Increase	Fair	2 studies 68 participants
Gluconolactone	C	Slight Increase	Fair	2 studies 68 participants
Niacinamide	C	Slight Increase	Fair	2 studies 49 participants
Niacinamide + Tranexamic Acid	C	Slight Increase	Fair	1 study 42 participants
Tartaric Acid	C	Slight Increase	Fair	1 study 11 participants
Niacinamide + Sunscreen	C	Slight Increase	Fair	1 study 120 participants
Lactic Acid	C	Slight Increase	Fair	1 study 11 participants
Hydroquinone	D	Slight Increase	Some	1 study 44 participants
Delta-Tocopherol Glucoside + Glycylglycine Oleamide + Retinal	D	Slight Increase	Some	1 study 57 participants
Arbutin + Galactomyces Ferment Filtrate + Niacinamide + Tranexamic Acid	D	Slight Increase	Some	1 study 44 participants
Pterostilbene	D	Potential Increase	Some	1 study 38 participants
Retinol	D	Potential Increase	Fair	1 study 36 participants
Arbutin + Bisabolol + Niacinamide + Retinal	D	Potential Increase	Some	1 study 33 participants
Tretinoin	D	Potential Increase	Fair	1 study 167 participants
Alpha-Ketoglutarate	D	Potential Increase	Some	1 study 30 participants
Hyaluronic Acid + Thiamidol	D	Potential Increase	Some	1 study 30 participants
Linoleic Acid + Niacinamide + Oxidised Glutathione + Oxyresveratrol + Tranexamic Acid	D	Potential Increase	Some	1 study 26 participants
Centella Asiatica Extract + Galactomyces Ferment Filtrate + Panthenol	D	Potential Increase	Good	1 study 51 participants
Ascorbic Acid	D	Potential Increase	Fair	1 study 19 participants
SIG-1273	D	Potential Increase	Some	1 study 29 participants

Products

Show 17 more products
Product	Grade	Effect	Evidence	Studies
Cellex-C High-Potency Serum	C	Slight Increase	Fair	1 study 19 participants
Imedeen Derma One	C	Slight Increase	Fair	1 study 152 participants
Aestura Regederm RX White Project	C	Slight Increase	Fair	1 study 42 participants
Avene A-OXitive NIGHT Peeling Cream	D	Slight Increase	Some	1 study 57 participants
Imedeen Man-Age-Ment	D	Potential Increase	Some	1 study 41 participants
Isdinceutics Melatonik	D	Potential Increase	Some	1 study 24 participants
Isdinceutics Melaclear	D	Potential Increase	Some	1 study 10 participants
RoC Retinol Correxion Deep Wrinkle Night Cream	D	Potential Increase	Fair	1 study 36 participants
Renova	D	Potential Increase	Fair	1 study 167 participants
Olay Total Effects 7X Visible Anti-Aging Vitamin Complex	D	Potential Increase	Some	1 study 46 participants
Revision Skincare Retinol Complete + Revision Skincare Vitamin C Lotion 30%	D	Potential Increase	Some	1 study 44 participants
Eucerin UltraWHITE Spotless Double Booster Serum	D	Potential Increase	Some	1 study 30 participants
ISDIN FotoUltra 100 Spot Prevent Fusion Fluid + Isdinceutics Pigment Expert	D	Potential Increase	Some	1 study 11 participants
Neora Age IQ Night Cream	D	Potential Increase	Some	1 study 37 participants
Avene DermAbsolu Serum	D	Potential Increase	Some	1 study 41 participants
PteroWhite	D	Potential Increase	Some	1 study 38 participants
Imedeen	D	Potential Increase	Some	1 study 6 participants
SkinAx²	D	Potential Increase	Some	1 study 35 participants
La Roche-Posay Active C	D	Potential Increase	Fair	1 study 19 participants
Burt's Bees Renewal Refining Cleanser + Burt's Bees Renewal Moisturizing Cream	D	Potential Increase	Some	1 study 60 participants
Imedeen Time Perfection	E	Mixed Effect	Some	3 studies 287 participants
Eucerin Anti-Pigment Dual Serum + Eucerin Anti-Pigment Day SPF30 + Eucerin Anti-Pigment Night	E	Mixed Effect	Some	2 studies 112 participants

Treatments

Coming soon.

Skincare treatments can penetrate more deeply into the skin to provide faster, more dramatic and longer-lasting results than topical products, but they are also much more expensive.

Review all of the scientific evidence before spending thousands of dollars on treatments that won't work, or that make your skin worse due to the side effects.

Log in to register your interest in knowing when information on skincare treatments becomes available on Wisderm.com, and get a 20% discount on launch!

2 Studies Found

Intervention	Glycolic Acid
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	28 days
Participants	11

Intervention	Glycolic Acid
Concern	Skin Brightness
Subject Type	Human
Trial Design	Single-Blind Non-Randomised Controlled
Trial Duration	84 days
Participants	57

2 Studies Found

Intervention	Gluconolactone
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	28 days
Participants	11

Intervention	Gluconolactone
Concern	Skin Brightness
Subject Type	Human
Trial Design	Single-Blind Non-Randomised Controlled
Trial Duration	84 days
Participants	57

2 Studies Found

Intervention	Niacinamide
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	56 days
Participants	138

Intervention	Niacinamide
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	84 days
Participants	50

1 Study Found

Intervention	Niacinamide + Tranexamic Acid
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	56 days
Participants	42

1 Study Found

Intervention	Tartaric Acid
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	28 days
Participants	11

1 Study Found

Intervention	Niacinamide + Sunscreen
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	56 days
Participants	138

1 Study Found

Intervention	Lactic Acid
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	28 days
Participants	11

1 Study Found

Intervention	Hydroquinone
Concern	Skin Brightness
Subject Type	Human
Trial Design	Randomised Controlled
Trial Duration	28 days
Participants	44

1 Study Found

Intervention	Delta-Tocopherol Glucoside + Glycylglycine Oleamide + Retinal
Concern	Skin Brightness
Subject Type	Human
Trial Design	Open-Label Randomised Controlled
Trial Duration	56 days
Participants	57

1 Study Found

Intervention	Arbutin + Galactomyces Ferment Filtrate + Niacinamide + Tranexamic Acid
Concern	Skin Brightness
Subject Type	Human
Trial Design	Randomised Controlled
Trial Duration	28 days
Participants	44

1 Study Found

Intervention	Pterostilbene
Concern	Skin Brightness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Controlled
Trial Duration	56 days
Participants	39

1 Study Found

Intervention	Retinol
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	56 days
Participants	64

1 Study Found

Intervention	Arbutin + Bisabolol + Niacinamide + Retinal
Concern	Skin Brightness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Uncontrolled
Trial Duration	60 days
Participants	35

1 Study Found

Intervention	Tretinoin
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	168 days
Participants	299

1 Study Found

Intervention	Alpha-Ketoglutarate
Concern	Skin Brightness
Subject Type	Human
Trial Design	Non-Randomised Controlled
Trial Duration	56 days
Participants	30

1 Study Found

Intervention	Hyaluronic Acid + Thiamidol
Concern	Skin Brightness
Subject Type	Human
Trial Design	Single-Blind Randomised Controlled
Trial Duration	84 days
Participants	30

1 Study Found

Intervention	Linoleic Acid + Niacinamide + Oxidised Glutathione + Oxyresveratrol + Tranexamic Acid
Concern	Skin Brightness
Subject Type	Human
Trial Design	Non-Randomised Uncontrolled
Trial Duration	84 days
Participants	26

1 Study Found

Intervention	Centella Asiatica Extract + Galactomyces Ferment Filtrate + Panthenol
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	56 days
Participants	51

1 Study Found

Intervention	Ascorbic Acid
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	168 days
Participants	20

1 Study Found

Intervention	SIG-1273
Concern	Skin Brightness
Subject Type	Human
Trial Design	Non-Randomised Uncontrolled
Trial Duration	28 days
Participants	31

1 Study Found

Intervention	Cellex-C High-Potency Serum
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	84 days
Participants	28

1 Study Found

Intervention	Imedeen Derma One
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	112 days
Participants	201

1 Study Found

Intervention	Aestura Regederm RX White Project
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	56 days
Participants	42

1 Study Found

Intervention	Avene A-OXitive NIGHT Peeling Cream
Concern	Skin Brightness
Subject Type	Human
Trial Design	Open-Label Randomised Controlled
Trial Duration	56 days
Participants	57

1 Study Found

Intervention	Imedeen Man-Age-Ment
Concern	Skin Brightness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Uncontrolled
Trial Duration	210 days
Participants	47

1 Study Found

Intervention	Isdinceutics Melatonik
Concern	Skin Brightness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Controlled
Trial Duration	168 days
Participants	24

1 Study Found

Intervention	Isdinceutics Melaclear
Concern	Skin Brightness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Uncontrolled
Trial Duration	84 days
Participants	10

1 Study Found

Intervention	RoC Retinol Correxion Deep Wrinkle Night Cream
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	56 days
Participants	64

1 Study Found

Intervention	Renova
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	168 days
Participants	299

1 Study Found

Intervention	Olay Total Effects 7X Visible Anti-Aging Vitamin Complex
Concern	Skin Brightness
Subject Type	Human
Trial Design	Single-Blind Randomised Controlled
Trial Duration	28 days
Participants	50

1 Study Found

Intervention	Revision Skincare Retinol Complete + Revision Skincare Vitamin C Lotion 30%
Concern	Skin Brightness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Uncontrolled
Trial Duration	84 days
Participants	44

1 Study Found

Intervention	Eucerin UltraWHITE Spotless Double Booster Serum
Concern	Skin Brightness
Subject Type	Human
Trial Design	Single-Blind Randomised Controlled
Trial Duration	84 days
Participants	30

1 Study Found

Intervention	ISDIN FotoUltra 100 Spot Prevent Fusion Fluid + Isdinceutics Pigment Expert
Concern	Skin Brightness
Subject Type	Human
Trial Design	Single-Blind Non-Randomised Uncontrolled
Trial Duration	84 days
Participants	12

1 Study Found

Intervention	Neora Age IQ Night Cream
Concern	Skin Brightness
Subject Type	Human
Trial Design	Non-Randomised Uncontrolled
Trial Duration	56 days
Participants	39

1 Study Found

Intervention	Avene DermAbsolu Serum
Concern	Skin Brightness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Uncontrolled
Trial Duration	56 days
Participants	43

1 Study Found

Intervention	PteroWhite
Concern	Skin Brightness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Controlled
Trial Duration	56 days
Participants	39

1 Study Found

Intervention	Imedeen
Concern	Skin Brightness
Subject Type	Human
Trial Design	Non-Randomised Uncontrolled
Trial Duration	90 days
Participants	6

1 Study Found

Intervention	SkinAx²
Concern	Skin Brightness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Uncontrolled
Trial Duration	56 days
Participants	35

1 Study Found

Intervention	La Roche-Posay Active C
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	168 days
Participants	20

1 Study Found

Intervention	Burt's Bees Renewal Refining Cleanser + Burt's Bees Renewal Moisturizing Cream
Concern	Skin Brightness
Subject Type	Human
Trial Design	Non-Randomised Uncontrolled
Trial Duration	28 days
Participants	60

3 Studies Found

Intervention	Imedeen Time Perfection
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	84 days
Participants	91

Intervention	Imedeen Time Perfection
Concern	Skin Brightness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Uncontrolled
Trial Duration	120 days
Participants	50

Intervention	Imedeen Time Perfection
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	168 days
Participants	194

2 Studies Found

Intervention	Eucerin Anti-Pigment Dual Serum + Eucerin Anti-Pigment Day SPF30 + Eucerin Anti-Pigment Night
Concern	Skin Brightness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Uncontrolled
Trial Duration	84 days
Participants	117

Intervention	Eucerin Anti-Pigment Dual Serum + Eucerin Anti-Pigment Day SPF30 + Eucerin Anti-Pigment Night
Concern	Skin Brightness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	84 days
Participants	123

Latest Research

Skin Brightness

Coming soon.

2 Studies Found

Alpha hydroxyacids modulate stratum corneum barrier function

A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen

2 Studies Found

Alpha hydroxyacids modulate stratum corneum barrier function

A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen

2 Studies Found

The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer

Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin

1 Study Found

Reduction in facial hyperpigmentation after treatment with a combination of topical niacinamide and tranexamic acid: a randomized, double-blind, vehicle-controlled trial

1 Study Found

Alpha hydroxyacids modulate stratum corneum barrier function

1 Study Found

The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer

1 Study Found

Alpha hydroxyacids modulate stratum corneum barrier function

1 Study Found

Randomized control trial outcomes of tranexamic acid combination serum as a depigmenting agent for the use in healthy individuals

1 Study Found

Antiaging efficacy of a retinaldehyde-based cream compared with glycolic acid peel sessions: A randomized controlled study

1 Study Found

Randomized control trial outcomes of tranexamic acid combination serum as a depigmenting agent for the use in healthy individuals

1 Study Found

An Open-Label Single-Arm, Monocentric Study Assessing the Efficacy and Safety of Natural Pterostilbene (Pterocarpus marsupium) for Skin Brightening and Antiaging Effects

1 Study Found

One-year topical stabilized retinol treatment improves photodamaged skin in a double-blind, vehicle-controlled trial

1 Study Found

A novel cream formulation containing nicotinamide 4%, arbutin 3%, bisabolol 1%, and retinaldehyde 0.05% for treatment of epidermal melasma

1 Study Found

Topical tretinoin for treatment of photodamaged skin. A multicenter study

1 Study Found

The study of skin hydration, anti-wrinkles function improvement of anti-aging cream with alpha-ketoglutarate

1 Study Found

Isobutylamido thiazolyl resorcinol for prevention of UVB-induced hyperpigmentation

1 Study Found

Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial

1 Study Found

The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color

1 Study Found

Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo

1 Study Found

In vitro and clinical evaluation of SIG1273: a cosmetic functional ingredient with a broad spectrum of anti-aging and antioxidant activities

1 Study Found

Use of topical ascorbic acid and its effects on photodamaged skin topography

1 Study Found

A Randomized, Double-blind, Placebo-controlled Clinical Trial Evaluating an Oral Anti-aging Skin Care Supplement for Treating Photodamaged Skin

1 Study Found

Reduction in facial hyperpigmentation after treatment with a combination of topical niacinamide and tranexamic acid: a randomized, double-blind, vehicle-controlled trial

1 Study Found

Antiaging efficacy of a retinaldehyde-based cream compared with glycolic acid peel sessions: A randomized controlled study

1 Study Found

Assessment of clinical effects and safety of an oral supplement based on marine protein, vitamin C, grape seed extract, zinc, and tomato extract in the improvement of visible signs of skin aging in men

1 Study Found

Efficacy and safety of a 3-in-1 antiaging night facial serum containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate through clinical and histological analysis

1 Study Found

Brightening and Improvement of Facial Skin Quality in Healthy Female Subjects With Moderate Hyperpigmentation or Dark Spots and Moderate Facial Aging

1 Study Found

One-year topical stabilized retinol treatment improves photodamaged skin in a double-blind, vehicle-controlled trial

1 Study Found

Topical tretinoin for treatment of photodamaged skin. A multicenter study

1 Study Found

Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea

1 Study Found

An Open Label Clinical Trial to Evaluate the Efficacy and Tolerance of a Retinol and Vitamin C Facial Regimen in Women With Mild-to-Moderate Hyperpigmentation and Photodamaged Facial Skin

1 Study Found

Isobutylamido thiazolyl resorcinol for prevention of UVB-induced hyperpigmentation

1 Study Found

An open-label, investigator-initiated, single-center, prospective, pilot clinical study to evaluate the efficacy of a skin whitening serum applied twice daily combined with a spot-preventing SPF50+ sunscreen in healthy female subjects with melasma hyperpigmentation

1 Study Found

SIG-1273 protects skin against urban air pollution and when formulated in AgeIQ™ Night Cream anti-aging benefits clinically demonstrated

1 Study Found

Efficacy of a Dermocosmetic Serum Combining Bakuchiol and Vanilla Tahitensis Extract to Prevent Skin Photoaging in vitro and to Improve Clinical Outcomes for Naturally Aged Skin

1 Study Found

An Open-Label Single-Arm, Monocentric Study Assessing the Efficacy and Safety of Natural Pterostilbene (Pterocarpus marsupium) for Skin Brightening and Antiaging Effects

1 Study Found

An oral approach to the treatment of photodamaged skin: a pilot study

1 Study Found