Prospective, randomized, double-blind clinical study of split-body comparison of topical hydroquinone and hexylresorcinol for skin pigment appearance

Study Design

Subject Type

Human

Trial Design

Double-Blind, Randomised, Controlled

Trial Duration

84 days

Participants

32 (29 completed)

Age Range

35-65 years

Efficacy

Intervention(s)			Outcome		Method		Effect	Description
Hydroquinone			Hyperpigmentation		Clinical grading		🠫	Sign in to read for free
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Hexylresorcinol			Hyperpigmentation		Clinical grading		🠫	Sign in to read for free
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Hexylresorcinol			Skin Redness		Colorimeter		🠩	Sign in to read for free
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Hydroquinone			Skin Redness		Colorimeter		🠩	Sign in to read for free
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Hexylresorcinol			Skin Redness		Colorimeter		🠫	Sign in to read for free
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Hydroquinone			Skin Redness		Colorimeter		🠫	Sign in to read for free
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Hydroquinone			Wrinkles		Clinical grading		–	Sign in to read for free
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Hexylresorcinol			Wrinkles		Clinical grading		–	Sign in to read for free
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Mechanisms

Intervention(s)			Outcome		Method		Effect	Description
Hexylresorcinol			Melanin		Colorimeter		🠫	Sign in to read for free
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Hydroquinone			Melanin		Colorimeter		🠫	Sign in to read for free
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Side Effects

Intervention(s)			Outcome		Effect	Description
Hexylresorcinol			Irritation		⇧	Sign in to read for free
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Hydroquinone			Irritation		–	Sign in to read for free
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Hexylresorcinol			Rash		⇧	Sign in to read for free
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Hydroquinone			Rash		–	Sign in to read for free
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Hexylresorcinol			Skin Discomfort		–	Sign in to read for free
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Hydroquinone			Skin Discomfort		–	Sign in to read for free
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Study Summary

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