Apigenin is among the most abundant flavonoids found in a variety of fruits and vegetables, including parsley, chamomile and celery. It is also a component of red wine and beer (R).
Apigenin is not very soluble in water. As a result, apigenin in conventional topical formulations such as ointments or tinctures penetrates the skin poorly. However, loading apigenin in ethosomes improves its skin deposition and transdermal permeation (R).
Outcome | Grade | Effect | Studies | |||||||
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Skin Elasticity |
B
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Skin Hydration |
B
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Skin Smoothness |
B
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Wrinkles |
B
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Skin Density |
B
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Outcome | Grade | Effect | Studies | |||||||
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Cellular Senescence |
B
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Collagenase |
B
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Cell Viability |
D
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