Skin Firmness

Ingredients

Show 4 more ingredients
Ingredient	Grade	Effect	Evidence	Studies
Retinol	C	Slight Increase	Fair	1 study 36 participants
Glycolic Acid	C	Slight Increase	Fair	2 studies 63 participants
Delta-Tocopherol Glucoside + Glycylglycine Oleamide + Retinal	D	Slight Increase	Some	1 study 57 participants
Gluconolactone	D	Slight Increase	Some	1 study 57 participants
Retinal	D	Potential Increase	Some	1 study 40 participants
Gluconolactone + Glycolic Acid + Lactobionic Acid	D	Potential Increase	Some	1 study 29 participants
Alpha-Ketoglutarate	D	Potential Increase	Some	1 study 30 participants
SIG-1273	D	Potential Increase	Some	1 study 29 participants
Lactic Acid	D	Potential Increase	Some	1 study 6 participants

Products

Show 6 more products
Product	Grade	Effect	Evidence	Studies
Tricutan	C	Notable Increase	Fair	1 study 25 participants
Dermyn	C	Notable Increase	Fair	1 study 25 participants
RoC Retinol Correxion Deep Wrinkle Night Cream	C	Slight Increase	Fair	1 study 36 participants
Viscoderm Pearls	D	Slight Increase	Some	1 study 30 participants
Avene A-OXitive NIGHT Peeling Cream	D	Slight Increase	Some	1 study 57 participants
Isdinceutics Melatonik	D	Potential Increase	Some	1 study 39 participants
SkinAx²	D	Potential Increase	Some	1 study 34 participants
Neora Age IQ Night Cream	D	Potential Decrease	Some	1 study 37 participants
Revision Skincare Retinol Complete + Revision Skincare Vitamin C Lotion 30%	D	Potential Increase	Some	1 study 44 participants
Avene DermAbsolu Serum	D	Potential Increase	Some	1 study 41 participants
Imedeen Time Perfection	E	No Effect	Fair	1 study 72 participants

Treatments

Coming soon.

Skincare treatments can penetrate more deeply into the skin to provide faster, more dramatic and longer-lasting results than topical products, but they are also much more expensive.

Review all of the scientific evidence before spending thousands of dollars on treatments that won't work, or that make your skin worse due to the side effects.

Log in to register your interest in knowing when information on skincare treatments becomes available on Wisderm.com, and get a 20% discount on launch!

1 Study Found

Intervention	Retinol
Concern	Skin Firmness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	56 days
Participants	64

2 Studies Found

Intervention	Glycolic Acid
Concern	Skin Firmness
Subject Type	Human
Trial Design	Single-Blind Non-Randomised Controlled
Trial Duration	84 days
Participants	57

Intervention	Glycolic Acid
Concern	Skin Firmness
Subject Type	Human
Trial Design	Non-Randomised Controlled
Trial Duration	42 days
Participants	10

1 Study Found

Intervention	Delta-Tocopherol Glucoside + Glycylglycine Oleamide + Retinal
Concern	Skin Firmness
Subject Type	Human
Trial Design	Open-Label Randomised Controlled
Trial Duration	56 days
Participants	57

1 Study Found

Intervention	Gluconolactone
Concern	Skin Firmness
Subject Type	Human
Trial Design	Single-Blind Non-Randomised Controlled
Trial Duration	84 days
Participants	57

1 Study Found

Intervention	Retinal
Concern	Skin Firmness
Subject Type	Human
Trial Design	Non-Randomised Uncontrolled
Trial Duration	365 days
Participants	44

1 Study Found

Intervention	Gluconolactone + Glycolic Acid + Lactobionic Acid
Concern	Skin Firmness
Subject Type	Human
Trial Design	Non-Randomised Uncontrolled
Trial Duration	84 days
Participants	30

1 Study Found

Intervention	Alpha-Ketoglutarate
Concern	Skin Firmness
Subject Type	Human
Trial Design	Non-Randomised Controlled
Trial Duration	56 days
Participants	30

1 Study Found

Intervention	SIG-1273
Concern	Skin Firmness
Subject Type	Human
Trial Design	Non-Randomised Uncontrolled
Trial Duration	28 days
Participants	31

1 Study Found

Intervention	Lactic Acid
Concern	Skin Firmness
Subject Type	Human
Trial Design	Non-Randomised Controlled
Trial Duration	42 days
Participants	10

1 Study Found

Intervention	Tricutan
Concern	Skin Firmness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	28 days
Participants	28

1 Study Found

Intervention	Dermyn
Concern	Skin Firmness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	28 days
Participants	28

1 Study Found

Intervention	RoC Retinol Correxion Deep Wrinkle Night Cream
Concern	Skin Firmness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	56 days
Participants	64

1 Study Found

Intervention	Viscoderm Pearls
Concern	Skin Firmness
Subject Type	Human
Trial Design	Open-Label Randomised Controlled
Trial Duration	28 days
Participants	30

1 Study Found

Intervention	Avene A-OXitive NIGHT Peeling Cream
Concern	Skin Firmness
Subject Type	Human
Trial Design	Open-Label Randomised Controlled
Trial Duration	56 days
Participants	57

1 Study Found

Intervention	Isdinceutics Melatonik
Concern	Skin Firmness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Uncontrolled
Trial Duration	84 days
Participants	103

1 Study Found

Intervention	SkinAx²
Concern	Skin Firmness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Uncontrolled
Trial Duration	56 days
Participants	35

1 Study Found

Intervention	Neora Age IQ Night Cream
Concern	Skin Firmness
Subject Type	Human
Trial Design	Non-Randomised Uncontrolled
Trial Duration	56 days
Participants	39

1 Study Found

Intervention	Revision Skincare Retinol Complete + Revision Skincare Vitamin C Lotion 30%
Concern	Skin Firmness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Uncontrolled
Trial Duration	84 days
Participants	44

1 Study Found

Intervention	Avene DermAbsolu Serum
Concern	Skin Firmness
Subject Type	Human
Trial Design	Open-Label Non-Randomised Uncontrolled
Trial Duration	56 days
Participants	43

1 Study Found

Intervention	Imedeen Time Perfection
Concern	Skin Firmness
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	84 days
Participants	91

Latest Research

Coming soon.

1 Study Found

One-year topical stabilized retinol treatment improves photodamaged skin in a double-blind, vehicle-controlled trial

2 Studies Found

A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen

Comparative effectiveness of alpha-hydroxy acids on skin properties

1 Study Found

Antiaging efficacy of a retinaldehyde-based cream compared with glycolic acid peel sessions: A randomized controlled study

1 Study Found

A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen

1 Study Found

Efficacy of topical 0.05% retinaldehyde in skin aging by ultrasound and rheological techniques

1 Study Found

Anti-Aging Effects and Tolerability of High Strength Hydroxy Acids in Males with Moderate to Severe Photoaging

1 Study Found

The study of skin hydration, anti-wrinkles function improvement of anti-aging cream with alpha-ketoglutarate

1 Study Found

In vitro and clinical evaluation of SIG1273: a cosmetic functional ingredient with a broad spectrum of anti-aging and antioxidant activities

1 Study Found

Comparative effectiveness of alpha-hydroxy acids on skin properties

1 Study Found

Randomised, placebo-controlled, double-blind, split-face study on the clinical efficacy of Tricutan on skin firmness

1 Study Found

Randomised, placebo-controlled, double-blind, split-face study on the clinical efficacy of Tricutan on skin firmness

1 Study Found

One-year topical stabilized retinol treatment improves photodamaged skin in a double-blind, vehicle-controlled trial

1 Study Found

A dietary supplement improves facial photoaging and skin sebum, hydration and tonicity modulating serum fibronectin, neutrophil elastase 2, hyaluronic acid and carbonylated proteins

1 Study Found

Antiaging efficacy of a retinaldehyde-based cream compared with glycolic acid peel sessions: A randomized controlled study

1 Study Found

Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days

1 Study Found

Clinical effects of an oral supplement rich in antioxidants on skin radiance in women

1 Study Found

SIG-1273 protects skin against urban air pollution and when formulated in AgeIQ™ Night Cream anti-aging benefits clinically demonstrated

1 Study Found

An Open Label Clinical Trial to Evaluate the Efficacy and Tolerance of a Retinol and Vitamin C Facial Regimen in Women With Mild-to-Moderate Hyperpigmentation and Photodamaged Facial Skin

1 Study Found

Efficacy of a Dermocosmetic Serum Combining Bakuchiol and Vanilla Tahitensis Extract to Prevent Skin Photoaging in vitro and to Improve Clinical Outcomes for Naturally Aged Skin

1 Study Found

A placebo-controlled, double-blind clinical trial to evaluate the efficacy of Imedeen Time Perfection for improving the appearance of photodamaged skin

The study of skin hydration, anti-wrinkles function improvement of anti-aging cream with alpha-ketoglutarate (2022)

Efficacy of a Dermocosmetic Serum Combining Bakuchiol and Vanilla Tahitensis Extract to Prevent Skin Photoaging in vitro and to Improve Clinical Outcomes for Naturally Aged Skin (2020)

SIG-1273 protects skin against urban air pollution and when formulated in AgeIQ™ Night Cream anti-aging benefits clinically demonstrated (2019)

Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days (2019)

Antiaging efficacy of a retinaldehyde-based cream compared with glycolic acid peel sessions: A randomized controlled study (2018)