Itching

Ingredients

Ingredient	Grade	Effect	Evidence	Studies
Salicylic Acid	C	Slight Decrease	Fair	1 study 24 participants
Azelaic Acid	D	Potential Increase	Fair	15 studies 2093 participants
Ivermectin	D	Potential Decrease	Fair	2 studies 2665 participants
Metronidazole	E	No Effect	Fair	1 study 37 participants

Products

Product				Grade		Effect		Evidence		Studies
Salex Cream				C		Slight Decrease		Fair		1 study 24 participants
NeoStrata Problem Dry Skin Cream				C		Slight Decrease		Fair		1 study 24 participants

Treatments

Coming soon.

Skincare treatments can penetrate more deeply into the skin to provide faster, more dramatic and longer-lasting results than topical products, but they are also much more expensive.

Review all of the scientific evidence before spending thousands of dollars on treatments that won't work, or that make your skin worse due to the side effects.

Log in to register your interest in knowing when information on skincare treatments becomes available on Wisderm.com, and get a 20% discount on launch!

1 Study Found

Intervention	Salicylic Acid
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	14 days
Participants	25

15 Studies Found

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Single-Blind Randomised Controlled
Trial Duration	84 days
Participants	67

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	168 days
Participants	381

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	168 days
Participants	155

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	84 days
Participants	116

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	168 days
Participants	329

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Open-Label Randomised Controlled
Trial Duration	56 days
Participants	30

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	84 days
Participants	664

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	45 days
Participants	60

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Randomised Controlled
Trial Duration	56 days
Participants	85

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	105 days
Participants	40

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	112 days
Participants	401

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	112 days
Participants	961

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Single-Blind Randomised Controlled
Trial Duration	280 days
Participants	1258

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Single-Blind Randomised Controlled
Trial Duration	84 days
Participants	221

Intervention	Azelaic Acid
Concern	Itching
Subject Type	Human
Trial Design	Open-Label Non-Randomised Uncontrolled
Trial Duration	112 days
Participants	20

2 Studies Found

Intervention	Ivermectin
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	84 days
Participants	1371

Intervention	Ivermectin
Concern	Itching
Subject Type	Human
Trial Design	Single-Blind Randomised Controlled
Trial Duration	280 days
Participants	1258

1 Study Found

Intervention	Metronidazole
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	105 days
Participants	40

1 Study Found

Intervention	Salex Cream
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	14 days
Participants	25

1 Study Found

Intervention	NeoStrata Problem Dry Skin Cream
Concern	Itching
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	14 days
Participants	25

Latest Research

Coming soon.

1 Study Found

A double-blind, randomized clinical trial of 20% alpha/poly hydroxy acid cream to reduce scaling of lesions associated with moderate, chronic plaque psoriasis

15 Studies Found

An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patients

Clinical studies of 20% azelaic acid cream in the treatment of acne vulgaris. Comparison with vehicle and topical tretinoin

Double-blind comparison of azelaic acid and hydroquinone in the treatment of melasma

Double-blind comparison of azelaic acid 20% cream and its vehicle in treatment of papulo-pustular rosacea

The treatment of melasma. 20% azelaic acid versus 4% hydroquinone cream

Comparative study of therapeutic effects of 20% azelaic acid and hydroquinone 4% cream in the treatment of melasma

Efficacy and safety of azelaic acid (15%) gel as a new treatment for papulopustular rosacea: results from two vehicle-controlled, randomized phase III studies

Efficacy of topical azelaic acid gel in the treatment of mild-moderate acne vulgaris

Relationship between sebostatic activity, tolerability and efficacy of three topical drugs to treat mild to moderate acne

A comparison of topical azelaic acid 20% cream and topical metronidazole 0.75% cream in the treatment of patients with papulopustular rosacea

Azelaic acid foam 15% in the treatment of papulopustular rosacea: a randomized, double-blind, vehicle-controlled study

A phase 3 randomized, double-blind, vehicle-controlled trial of azelaic acid foam 15% in the treatment of papulopustular rosacea

Long-term safety of ivermectin 1% cream vs azelaic acid 15% gel in treating inflammatory lesions of rosacea: results of two 40-week controlled, investigator-blinded trials

A multicentre, randomized, single-blind, parallel-group study comparing the efficacy and tolerability of benzoyl peroxide 3%/clindamycin 1% with azelaic acid 20% in the topical treatment of mild-to-moderate acne vulgaris

The Efficacy and Safety of Azelaic Acid 15% Foam in the Treatment of Truncal Acne Vulgaris

2 Studies Found

Efficacy and safety of ivermectin 1% cream in treatment of papulopustular rosacea: results of two randomized, double-blind, vehicle-controlled pivotal studies

Long-term safety of ivermectin 1% cream vs azelaic acid 15% gel in treating inflammatory lesions of rosacea: results of two 40-week controlled, investigator-blinded trials

1 Study Found

A comparison of topical azelaic acid 20% cream and topical metronidazole 0.75% cream in the treatment of patients with papulopustular rosacea

1 Study Found

A double-blind, randomized clinical trial of 20% alpha/poly hydroxy acid cream to reduce scaling of lesions associated with moderate, chronic plaque psoriasis

1 Study Found

A double-blind, randomized clinical trial of 20% alpha/poly hydroxy acid cream to reduce scaling of lesions associated with moderate, chronic plaque psoriasis

Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial (2021)

Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial (2021)

Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial (2021)

Effective reduction of post-inflammatory hyperpigmentation with the tyrosinase inhibitor isobutylamido-thiazolyl-resorcinol (Thiamidol) (2021)

Evaluation of the efficacy of cysteamine cream compared to hydroquinone in the treatment of melasma: A randomised, double-blinded trial (2021)