Multi-Center, Double-Blind, Vehicle-Controlled Clinical Trial of an Alpha and Beta Defensin-Containing Anti-Aging Skin Care Regimen With Clinical, Histopathologic, Immunohistochemical, Photographic, and Ultrasound Evaluation

Study Design

Subject Type

Human

Trial Design

Double-Blind, Randomised, Controlled

Trial Duration

84 days

Participants

46 (44 completed)

Age Range

41-71 years

Efficacy

Intervention(s)	Outcome	Method	Effect	Description
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum	Facial Pores	3D image analysis + clinical grading	🠫	Sign in to read for free
Sign in to read for free
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum	Peeling	Clinical grading	–	Sign in to read for free
Sign in to read for free
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum	Skin Barrier Function	DermaLab SkinLab Combo Suite	⇩	Sign in to read for free
Sign in to read for free
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum	Skin Brightness	DermaLab SkinLab Combo Suite	🠩	Sign in to read for free
Sign in to read for free
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum	Skin Elasticity	DermaLab SkinLab Combo Suite	⇧	Sign in to read for free
Sign in to read for free
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum	Skin Hydration	Clinical grading	⇧	Sign in to read for free
Sign in to read for free
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum	Skin Oiliness	3D image analysis	🠫	Sign in to read for free
Sign in to read for free
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum	Skin Sensitivity	Self-assessment	⇩	Sign in to read for free
Sign in to read for free
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum	Skin Smoothness	3D image analysis	🠩	Sign in to read for free
Sign in to read for free
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum	Skin Thickness	Histology + Ultrasound	🠩	Sign in to read for free
Sign in to read for free
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum	Wrinkles	3D image analysis + clinical grading	🠫	Sign in to read for free
Sign in to read for free

Mechanisms

Intervention(s)			Outcome		Method		Effect	Description
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum			Elastosis		Ultrasound		🠫	Sign in to read for free
Sign in to read for free

Side Effects

Intervention(s)	Outcome	Effect	Description
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum	Inflammation	–	Sign in to read for free
Sign in to read for free
DefenAge 2-Minute Reveal Masque + DefenAge 24/7 Barrier Balance Cream + DefenAge 8-in-1 BioSerum	Skin Redness	–	Sign in to read for free
Sign in to read for free

Study Summary