Peeling

Ingredients

Ingredient	Grade	Effect	Evidence	Studies
Salicylic Acid	C	Slight Decrease	Fair	1 study 24 participants
Retinol	C	Slight Increase	Fair	5 studies 170 participants
Niacinamide	D	Marked Decrease	Some	3 studies 94 participants
Petrolatum	D	Slight Increase	Some	1 study 15 participants
Gluconolactone + Glycolic Acid + Lactobionic Acid	D	Potential Increase	Some	1 study 29 participants

Products

Product	Grade	Effect	Evidence	Studies
Salex Cream	C	Slight Decrease	Fair	1 study 24 participants
NeoStrata Problem Dry Skin Cream	C	Slight Decrease	Fair	1 study 24 participants
Olay Total Effects 7X Visible Anti-Aging Vitamin Complex	D	Potential Decrease	Some	1 study 46 participants

Treatments

Coming soon.

Skincare treatments can penetrate more deeply into the skin to provide faster, more dramatic and longer-lasting results than topical products, but they are also much more expensive.

Review all of the scientific evidence before spending thousands of dollars on treatments that won't work, or that make your skin worse due to the side effects.

Log in to register your interest in knowing when information on skincare treatments becomes available on Wisderm.com, and get a 20% discount on launch!

1 Study Found

Intervention	Salicylic Acid
Concern	Peeling
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	14 days
Participants	25

5 Studies Found

Intervention	Retinol
Concern	Peeling
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	56 days
Participants	64

Intervention	Retinol
Concern	Peeling
Subject Type	Human
Trial Design	Double-Blind Non-Randomised Controlled
Trial Duration	308 days
Participants	355

Intervention	Retinol
Concern	Peeling
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	182 days
Participants	106

Intervention	Retinol
Concern	Peeling
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	168 days
Participants	36

Intervention	Retinol
Concern	Peeling
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	84 days
Participants	44

3 Studies Found

Intervention	Niacinamide
Concern	Peeling
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Participants	80

Intervention	Niacinamide
Concern	Peeling
Subject Type	Human
Trial Design	Single-Blind Non-Randomised Controlled
Trial Duration	56 days
Participants	28

Intervention	Niacinamide
Concern	Peeling
Subject Type	Human
Trial Design	Randomised Controlled
Trial Duration	84 days
Participants	48

1 Study Found

Intervention	Petrolatum
Concern	Peeling
Subject Type	Human
Trial Design	Single-Blind Non-Randomised Controlled
Trial Duration	56 days
Participants	28

1 Study Found

Intervention	Gluconolactone + Glycolic Acid + Lactobionic Acid
Concern	Peeling
Subject Type	Human
Trial Design	Non-Randomised Uncontrolled
Trial Duration	84 days
Participants	30

1 Study Found

Intervention	Salex Cream
Concern	Peeling
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	14 days
Participants	25

1 Study Found

Intervention	NeoStrata Problem Dry Skin Cream
Concern	Peeling
Subject Type	Human
Trial Design	Double-Blind Randomised Controlled
Trial Duration	14 days
Participants	25

1 Study Found

Intervention	Olay Total Effects 7X Visible Anti-Aging Vitamin Complex
Concern	Peeling
Subject Type	Human
Trial Design	Single-Blind Randomised Controlled
Trial Duration	28 days
Participants	50

Latest Research

Coming soon.

1 Study Found

A double-blind, randomized clinical trial of 20% alpha/poly hydroxy acid cream to reduce scaling of lesions associated with moderate, chronic plaque psoriasis

5 Studies Found

One-year topical stabilized retinol treatment improves photodamaged skin in a double-blind, vehicle-controlled trial

Tolerance profile of retinol, retinaldehyde and retinoic acid under maximized and long-term clinical conditions

Improvement of photoaged facial skin in middle-aged Japanese females by topical retinol (vitamin A alcohol): a vehicle-controlled, double-blind study

Improvement of naturally aged skin with vitamin A (retinol)

Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing

3 Studies Found

Topical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgaris

Moisturizing effects of topical nicotinamide on atopic dry skin

Topical nicotinamide for seborrheic dermatitis: an open randomized study

1 Study Found

Moisturizing effects of topical nicotinamide on atopic dry skin

1 Study Found

Anti-Aging Effects and Tolerability of High Strength Hydroxy Acids in Males with Moderate to Severe Photoaging

1 Study Found

A double-blind, randomized clinical trial of 20% alpha/poly hydroxy acid cream to reduce scaling of lesions associated with moderate, chronic plaque psoriasis

1 Study Found

A double-blind, randomized clinical trial of 20% alpha/poly hydroxy acid cream to reduce scaling of lesions associated with moderate, chronic plaque psoriasis

1 Study Found

Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea

Efficacy and safety of topical isobutylamido thiazolyl resorcinol (Thiamidol) vs. 4% hydroquinone cream for facial melasma: an evaluator-blinded, randomized controlled trial (2021)

Efficacy and safety of topical isobutylamido thiazolyl resorcinol (Thiamidol) vs. 4% hydroquinone cream for facial melasma: an evaluator-blinded, randomized controlled trial (2021)

A comparative study of topical 5% cysteamine versus 4% hydroquinone in the treatment of facial melasma in women (2020)

Clinical Evaluation of a Nature-Based Bakuchiol Anti-Aging Moisturizer for Sensitive Skin (2020)

A comparative study of topical 5% cysteamine versus 4% hydroquinone in the treatment of facial melasma in women (2020)